表面等离子体生物传感器：原理、设计与应用。

Surface plasmonic biosensors: principles, designs and applications.

机构信息

University of Electronic Science and Technology of China, Chengdu, China.

School of Sensing Science and Engineering, Shanghai Jiao Tong University, Shanghai, China.

出版信息

Analyst. 2023 Dec 4;148(24):6146-6160. doi: 10.1039/d3an01241g.

DOI:10.1039/d3an01241g

PMID:37921208

Abstract

Recently, surface plasmon resonance (SPR) biosensors have been widely used in environmental monitoring, food contamination detection and diagnosing medical conditions due to their superior sensitivity, label-free detection and rapid analysis speed. This paper briefly elaborates on the development history of SPR technology and introduces SPR signal sensing principles. A summary of recent applications of SPR sensors in different fields is highlighted, including their figures of merit and limitations. Finally, the personal perspectives and future development trends about sensor preparation and design are discussed in detail, which may be critical for improving the performance of SPR sensors.

摘要

最近，表面等离子体共振（SPR）生物传感器由于其超高的灵敏度、无标记检测和快速分析速度，在环境监测、食品污染检测和诊断医疗状况等领域得到了广泛的应用。本文简要阐述了 SPR 技术的发展历史，并介绍了 SPR 信号传感原理。重点总结了 SPR 传感器在不同领域的最新应用，包括其优缺点。最后，详细讨论了传感器制备和设计方面的个人观点和未来发展趋势，这对于提高 SPR 传感器的性能可能是至关重要的。