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在集成有电池供电热箔加热器的低成本微流控平台上进行便携式原位温度相关光谱分析。

Portable in situ temperature-dependent spectroscopy on a low-cost microfluidic platform integrated with a battery-powered thermofoil heater.

作者信息

Katla Sai Krishna, Zhou Wan, Tavakoli Hamed, Padilla Méndez Elvia Lilia, Li Xiujun

机构信息

Department of Chemistry and Biochemistry, University of Texas at El Paso, El Paso, Texas, USA.

Border Biomedical Research Center, & Forensic Science, University of Texas at El Paso, El Paso, Texas, USA.

出版信息

View (Beijing). 2023 Apr;4(2). doi: 10.1002/viw.20220053. Epub 2023 Jan 11.

DOI:10.1002/viw.20220053
PMID:37928779
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10621267/
Abstract

A low-cost microfluidic platform integrated with a flexible heater was developed for in situ temperature-dependent spectroscopic measurement at the point of care. After verifying the system by comparing on-chip spectroscopic measurement of methylene blue with the conventional spectroscopy, we demonstrated its applications in temperature-dependent absorption spectroscopy of a model biomolecule, curcumin. The system is portable, battery-powered and requires ultra-low volumes of analytes, which is highly suitable for point-of-care characterization.

摘要

开发了一种集成有柔性加热器的低成本微流控平台，用于在护理现场进行原位温度相关的光谱测量。通过将亚甲基蓝的芯片上光谱测量与传统光谱进行比较来验证该系统后，我们展示了其在模型生物分子姜黄素的温度相关吸收光谱中的应用。该系统便于携带、由电池供电且所需分析物体积超低，非常适合护理现场表征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ed8/10621267/7dbe62bad93c/nihms-1909489-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ed8/10621267/29f282a14ba0/nihms-1909489-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ed8/10621267/32013ca0a117/nihms-1909489-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ed8/10621267/6d2d91d11db0/nihms-1909489-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ed8/10621267/7dbe62bad93c/nihms-1909489-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ed8/10621267/29f282a14ba0/nihms-1909489-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ed8/10621267/32013ca0a117/nihms-1909489-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ed8/10621267/6d2d91d11db0/nihms-1909489-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ed8/10621267/7dbe62bad93c/nihms-1909489-f0004.jpg

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