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一种用于实时监测的基于树仿生微流体结构的全弹性可穿戴式电化学汗液检测系统。

A Fully Elastic Wearable Electrochemical Sweat Detection System of Tree-Bionic Microfluidic Structure for Real-Time Monitoring.

作者信息

Niu Jiaqi, Lin Shujing, Chen Di, Wang Zhitao, Cao Cheng, Gao Ang, Cui Shengsheng, Liu Yanlei, Hong Yuping, Zhi Xiao, Cui Daxiang

机构信息

School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, P. R. China.

School of Electronic Information and Electrical Engineering, Shanghai Engineering Research Center for Intelligent Diagnosis and Treatment Instrument, Shanghai Jiao Tong University, Shanghai, 200240, P. R. China.

出版信息

Small. 2024 Mar;20(11):e2306769. doi: 10.1002/smll.202306769. Epub 2023 Nov 6.

Abstract

Fresh sweat contains a diverse range of physiological indicators that can effectively reflect changes in the body. However, existing wearable sweat detection systems face challenges in efficiently collecting and detecting fresh sweat in real-time. Additionally, they often lack the necessary deformation capabilities, resulting in discomfort for the wearer. Here, a fully elastic wearable electrochemical sweat detection system is developed that integrates a sweat-collecting microfluidic chip, a multi-parameter electrochemical sensor, a micro-heater, and a sweat detection elastic circuit board system. The unique tree-bionic structure of the microfluidic chip significantly enhances the efficiency of fresh sweat collection and discharge, enabling real-time detection by the electrochemical sensors. The sweat multi-parameter electrochemical sensor offers high-precision and high-sensitivity measurements of sodium ions, potassium ions, lactate, and glucose. The electronic system is built on an elastic circuit board that matches perfectly to wrinkled skin, ensuring improved wearing comfort and enabling multi-channel data sampling, processing, and wireless transmission. This state-of-the-art system represents a significant advancement in the field of elastic wearable sweat detection and holds promising potential for extending its capabilities to the detection of other sweat markers or various wearable applications.

摘要

新鲜汗液包含多种生理指标,能够有效反映身体的变化。然而,现有的可穿戴汗液检测系统在实时高效收集和检测新鲜汗液方面面临挑战。此外,它们往往缺乏必要的变形能力,给佩戴者带来不适。在此,开发了一种全弹性可穿戴电化学汗液检测系统,该系统集成了汗液收集微流控芯片、多参数电化学传感器、微型加热器和汗液检测弹性电路板系统。微流控芯片独特的树状仿生结构显著提高了新鲜汗液的收集和排出效率,使电化学传感器能够进行实时检测。汗液多参数电化学传感器可对钠离子、钾离子、乳酸和葡萄糖进行高精度、高灵敏度的测量。电子系统基于与褶皱皮肤完美匹配的弹性电路板构建,确保了更高的佩戴舒适度,并实现了多通道数据采样、处理和无线传输。这种先进的系统代表了弹性可穿戴汗液检测领域的重大进步,并有望将其功能扩展到检测其他汗液标志物或各种可穿戴应用中。

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