Lemonnier F, Moatti N, Brivet M, Domange C, Gautier M
Biomedicine. 1979 Feb;30(1):52-6.
Some enzymatic activities were studied in long ter cultures of human liver cells : glucose-6-phosphatase, U.D.P. glucuronosyltransferase, phenylalanine 4-hydroxylase and tyrosine aminotransferase. Only weak tyrosine aminotransferase activity has been found in 12 subcultures, and it has not been increased by addition of corticoids. This tyrosine aminotransferase activity has been measured at different passages of the culture. Our results are compared with those found in literature. The different reasons which could explain the absence of liver specific biochemical functions have been discussed.
葡萄糖-6-磷酸酶、尿苷二磷酸葡糖醛酸基转移酶、苯丙氨酸4-羟化酶和酪氨酸转氨酶。在12次传代培养中仅发现了微弱的酪氨酸转氨酶活性，并且添加皮质激素后该活性并未增加。已在培养的不同传代阶段测量了这种酪氨酸转氨酶活性。将我们的结果与文献中的结果进行了比较。讨论了可能解释缺乏肝脏特异性生化功能的不同原因。
