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纳米工程提高维生素生物利用度及其应用:最新进展。

Enhancement in Biological Availability of Vitamins by Nano-engineering and its Applications: An Update.

机构信息

Faculty of Agricultural Sciences, GLA University, Mathura-281406, India.

Department of Dairy Science and Food Technology, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi-221005, India.

出版信息

Curr Pharm Biotechnol. 2024;25(12):1523-1537. doi: 10.2174/0113892010251234231025085759.

DOI:10.2174/0113892010251234231025085759
PMID:37936473
Abstract

Vitamin nano-engineering has been accomplished by synthesizing various nanostructures to improve their stability, bioavailability, shelf life, and functioning. This review provides a detailed description of recent advances in the art of encapsulation with high efficiency through the use of practical and logistic nano-engineering techniques such as nanofibres, nanogels, nanobeads, nanotubes, nanoparticles, nanoliposomes, and many other nanostructures. To demonstrate the interaction of molecules with nano-forms, the bioavailability of several vitamins such as B, C, E, A, D, and others in the form of nanostructures is explored. This review will provide a thorough understanding of how to improve bioavailability and nanostructure selection to extend the utility, shelf life, and structural stability of vitamins. While nanoencapsulation can improve vitamin stability and distribution, the materials employed in nanotechnologies may offer concerns if they are not sufficiently tested for safety. If nanoparticles are not adequately designed and evaluated, they may cause inflammation, oxidative stress, or other unwanted effects. Researchers and makers of nanomaterials and medication delivery systems should adhere to established rules and regulations. Furthermore, long-term studies are required to monitor any negative consequences that may result from the use of nanostructure.

摘要

通过合成各种纳米结构来提高其稳定性、生物利用度、保质期和功能,实现了维生素纳米工程。本综述详细描述了通过使用实际和逻辑纳米工程技术(如纳米纤维、纳米凝胶、纳米珠、纳米管、纳米颗粒、纳米脂质体和许多其他纳米结构)进行高效封装的最新进展。为了展示分子与纳米形式的相互作用,探索了几种维生素(如 B、C、E、A、D 等)以纳米结构形式的生物利用度。本综述将提供对如何提高生物利用度和纳米结构选择以延长维生素的效用、保质期和结构稳定性的全面理解。虽然纳米封装可以提高维生素的稳定性和分布,但如果纳米技术中使用的材料没有经过充分的安全性测试,可能会引起关注。如果纳米颗粒设计和评估不当,可能会引起炎症、氧化应激或其他不良影响。纳米材料和药物输送系统的研究人员和制造商应遵守既定的规则和法规。此外,需要进行长期研究以监测使用纳米结构可能产生的任何负面后果。

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本文引用的文献

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Current Applications of Liposomes for the Delivery of Vitamins: A Systematic Review.脂质体在维生素递送中的当前应用:一项系统评价。
Nanomaterials (Basel). 2023 May 5;13(9):1557. doi: 10.3390/nano13091557.
2
Encapsulation of Vitamins Using Nanoliposome: Recent Advances and Perspectives.利用纳米脂质体包封维生素:最新进展与展望
Adv Pharm Bull. 2023 Jan;13(1):48-68. doi: 10.34172/apb.2023.005. Epub 2021 Oct 10.
3
Nano-vitamin C: A promising candidate for therapeutic applications.纳米维生素 C:治疗应用的有前途候选物。
Biomed Pharmacother. 2023 Feb;158:114093. doi: 10.1016/j.biopha.2022.114093. Epub 2022 Dec 7.
4
Practical application of nanoencapsulated nutraceuticals in real food products; a systematic review.纳米封装营养保健品在实际食品中的实际应用;系统评价。
Adv Colloid Interface Sci. 2022 Jul;305:102690. doi: 10.1016/j.cis.2022.102690. Epub 2022 May 3.
5
Drug release study of the chitosan-based nanoparticles.基于壳聚糖的纳米颗粒的药物释放研究。
Heliyon. 2021 Dec 24;8(1):e08674. doi: 10.1016/j.heliyon.2021.e08674. eCollection 2022 Jan.
6
Fabrication, stability and rheological properties of zein/chitosan particles stabilized Pickering emulsions with antioxidant activities of the encapsulated vit-D.玉米醇溶蛋白/壳聚糖颗粒的制备、稳定性及流变性,以及包埋维生素 D 的抗氧化活性的皮克林乳液。
Int J Biol Macromol. 2021 Nov 30;191:803-810. doi: 10.1016/j.ijbiomac.2021.09.159. Epub 2021 Sep 29.
7
Encapsulation of folic acid (vitamin B) into sporopollenin microcapsules: Physico-chemical characterisation, in vitro controlled release and photoprotection study.叶酸(维生素 B)包封入花粉外壁微胶囊中:物理化学性质表征、体外控制释放和光保护研究。
Mater Sci Eng C Mater Biol Appl. 2021 Sep;128:112271. doi: 10.1016/j.msec.2021.112271. Epub 2021 Jun 24.
8
Guidance on risk assessment of nanomaterials to be applied in the food and feed chain: human and animal health.用于食品和饲料链的纳米材料风险评估指南:人类和动物健康
EFSA J. 2021 Aug 3;19(8):e06768. doi: 10.2903/j.efsa.2021.6768. eCollection 2021 Aug.
9
Nanotechnology: A novel tool to enhance the bioavailability of micronutrients.纳米技术:提高微量营养素生物利用度的新型工具。
Food Sci Nutr. 2021 May 4;9(6):3354-3361. doi: 10.1002/fsn3.2311. eCollection 2021 Jun.
10
Encapsulation and controlled release of vitamin C in modified cellulose nanocrystal/chitosan nanocapsules.维生素C在改性纤维素纳米晶体/壳聚糖纳米胶囊中的包封与控释
Curr Res Food Sci. 2021 Apr 2;4:215-223. doi: 10.1016/j.crfs.2021.03.010. eCollection 2021.