Faculty of Agricultural Sciences, GLA University, Mathura-281406, India.
Department of Dairy Science and Food Technology, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi-221005, India.
Curr Pharm Biotechnol. 2024;25(12):1523-1537. doi: 10.2174/0113892010251234231025085759.
Vitamin nano-engineering has been accomplished by synthesizing various nanostructures to improve their stability, bioavailability, shelf life, and functioning. This review provides a detailed description of recent advances in the art of encapsulation with high efficiency through the use of practical and logistic nano-engineering techniques such as nanofibres, nanogels, nanobeads, nanotubes, nanoparticles, nanoliposomes, and many other nanostructures. To demonstrate the interaction of molecules with nano-forms, the bioavailability of several vitamins such as B, C, E, A, D, and others in the form of nanostructures is explored. This review will provide a thorough understanding of how to improve bioavailability and nanostructure selection to extend the utility, shelf life, and structural stability of vitamins. While nanoencapsulation can improve vitamin stability and distribution, the materials employed in nanotechnologies may offer concerns if they are not sufficiently tested for safety. If nanoparticles are not adequately designed and evaluated, they may cause inflammation, oxidative stress, or other unwanted effects. Researchers and makers of nanomaterials and medication delivery systems should adhere to established rules and regulations. Furthermore, long-term studies are required to monitor any negative consequences that may result from the use of nanostructure.
通过合成各种纳米结构来提高其稳定性、生物利用度、保质期和功能,实现了维生素纳米工程。本综述详细描述了通过使用实际和逻辑纳米工程技术(如纳米纤维、纳米凝胶、纳米珠、纳米管、纳米颗粒、纳米脂质体和许多其他纳米结构)进行高效封装的最新进展。为了展示分子与纳米形式的相互作用,探索了几种维生素(如 B、C、E、A、D 等)以纳米结构形式的生物利用度。本综述将提供对如何提高生物利用度和纳米结构选择以延长维生素的效用、保质期和结构稳定性的全面理解。虽然纳米封装可以提高维生素的稳定性和分布,但如果纳米技术中使用的材料没有经过充分的安全性测试,可能会引起关注。如果纳米颗粒设计和评估不当,可能会引起炎症、氧化应激或其他不良影响。纳米材料和药物输送系统的研究人员和制造商应遵守既定的规则和法规。此外,需要进行长期研究以监测使用纳米结构可能产生的任何负面后果。