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肥胖症手术后妊娠的缺铁性贫血:病因、危险因素及处理方法。

Iron Deficiency Anemia in Pregnancy after Bariatric Surgery: Etiology, Risk Factors, and How to Manage It.

机构信息

Departamento de Tocoginecologia da Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brazil.

出版信息

Rev Bras Ginecol Obstet. 2023 Oct;45(10):e562-e567. doi: 10.1055/s-0043-1776026. Epub 2023 Nov 9.

DOI:10.1055/s-0043-1776026
PMID:37944922
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10635785/
Abstract

OBJECTIVE

Pregnancy after bariatric surgery is a reality of the 21 century and therefore is essential that all obstetricians know how to manage it. The most prevalent nutritional deficiency is iron deficiency and, consequently, anemia. Although bariatric surgery and pregnancy are already risk factors for anemia, we evaluated in our study if there were any other risk factors and actions to improve hemoglobin levels in this population.

METHODS

We performed a retrospective cohort study, and performed frequency measurements and analyzes of odds ratio, X and Fisher exact test to evaluate the risk factors.

RESULTS

We evaluated 44 pregnancies after bariatric surgery, with an incidence of anemia of 62%, and the only identifiable risk factor for anemia was being black. As for the treatment, the iron salt used for oral supplementation did not associate with anemia risk, and in 27% of the patients, the adjustment of the oral dosage was enough for improvement in hemoglobin levels, but in 36% supplementation with intravenous iron was necessary.

CONCLUSION

Being black is a risk factor for anemia. The type of iron salt does not correlate with the incidence of anemia, and for the treatment and improvement of iron dosages, it seems an effective increase in iron intake.

摘要

目的

肥胖症手术治疗后的妊娠是 21 世纪的现实情况,因此所有妇产科医生都必须掌握相关的处理方法。最常见的营养缺乏是缺铁,进而导致贫血。尽管肥胖症手术治疗和妊娠本身就是贫血的危险因素,但我们在本研究中评估了该人群中是否存在其他的贫血危险因素和改善血红蛋白水平的措施。

方法

我们进行了一项回顾性队列研究,进行了频率测量和比值比、X 和 Fisher 确切检验分析,以评估危险因素。

结果

我们评估了 44 例肥胖症手术后的妊娠,贫血发生率为 62%,唯一可识别的贫血危险因素是黑种人。至于治疗,口服补铁剂的使用与贫血风险无关,在 27%的患者中,调整口服剂量足以提高血红蛋白水平,但在 36%的患者中需要静脉补铁。

结论

黑种人是贫血的一个危险因素。铁盐的类型与贫血的发生率无关,对于治疗和改善铁剂量,似乎增加铁的摄入量是有效的。

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