Department of Plastic and Reconstructive Surgery, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Department of Plastic and Reconstructive Surgery, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, Republic of Korea.
Int J Low Extrem Wounds. 2024 Mar;23(1):27-32. doi: 10.1177/15347346231210144. Epub 2023 Nov 9.
Diabetic foot ulcer represents the primary cause of hospital admissions, amputations, and mortality in diabetic patients. The development of diabetic foot ulcers is influenced by peripheral neuropathy, infection, and ischemia, with diabetes contributing to peripheral artery disease. Free tissue transfer combined with revascularisation of the lower extremity provides the potential opportunity for limb salvage in individuals with lower extremity defects due to critical limb ischemia and diabetic foot.
糖尿病足溃疡是导致糖尿病患者住院、截肢和死亡的主要原因。糖尿病足溃疡的发生发展与外周神经病变、感染和缺血有关，糖尿病可导致外周动脉疾病。游离组织移植联合下肢血运重建为因严重肢体缺血和糖尿病足而导致下肢缺陷的患者提供了肢体挽救的机会。
