Hu Jinhua, Liang Yongxue, Huang Xueyao, Chen Guangxue, Liu Dingrong, Chen Zhuangzhuang, Fang Zheng, Chen Xuelong
State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China.
School of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Polymers (Basel). 2023 Oct 30;15(21):4272. doi: 10.3390/polym15214272.
Biocompatible particle-stabilized emulsions have gained significant attention in the biomedical industry. In this study, we employed dynamic high-pressure microfluidization (HPM) to prepare a biocompatible particle emulsion, which effectively enhances the thermal stability of core materials without the addition of any chemical additives. The results demonstrate that the HPM-treated particle-stabilized emulsion forms an interface membrane with high expansion and viscoelastic properties, thus preventing core material agglomeration at elevated temperatures. Furthermore, the particle concentration used for constructing the emulsion gel network significantly impacts the overall strength and stability of the material while possessing the ability to inhibit oxidation of the thermosensitive core material. This investigation explores the influence of particle concentration on the stability of particle-stabilized emulsion gels, thereby providing valuable insights for the design, improvement, and practical applications of innovative clean label emulsions, particularly in the embedding and delivery of thermosensitive core materials.
生物相容性颗粒稳定乳液在生物医学行业中受到了广泛关注。在本研究中，我们采用动态高压微流化技术（HPM）制备了一种生物相容性颗粒乳液，该乳液在不添加任何化学添加剂的情况下有效提高了核心材料的热稳定性。结果表明，经HPM处理的颗粒稳定乳液形成了具有高膨胀性和粘弹性的界面膜，从而防止了核心材料在高温下团聚。此外，用于构建乳液凝胶网络的颗粒浓度对材料的整体强度和稳定性有显著影响，同时具有抑制热敏核心材料氧化的能力。本研究探讨了颗粒浓度对颗粒稳定乳液凝胶稳定性的影响，从而为创新型清洁标签乳液的设计、改进及实际应用提供了有价值的见解，特别是在热敏核心材料的包埋和递送方面。
