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子痫前期及其在埃塞俄比亚的决定因素:系统评价和荟萃分析。

Preeclampsia and its determinants in Ethiopia: A systematic review and meta-analysis.

机构信息

Department of Midwifery, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.

Department of Psychiatry, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.

出版信息

PLoS One. 2023 Nov 14;18(11):e0287038. doi: 10.1371/journal.pone.0287038. eCollection 2023.

DOI:10.1371/journal.pone.0287038
PMID:37963147
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10645334/
Abstract

BACKGROUND

Preeclampsia is a serious condition that is linked to poor perinatal outcomes. In Ethiopia, the overall prevalence of preeclampsia and its associated factors is uncertain. Therefore, the purpose of this review was to find the prevalence of pre-eclampsia and its determinants in Ethiopia.

METHODS

To find primary studies, PubMed, Google Scholar, HINAR, Scopus, the Web of Sciences, and grey literature searches were used between January 1, 2013, and January 1, 2023, in Ethiopia. A Microsoft Excel sheet was used to extract data. The pooled prevalence of pre-eclampsia was predicted using a random-effect model.

RESULTS

Twenty-nine studies were included. The pooled prevalence of pre-eclampsia was 11.51% (95% CI: 8.41, 14.61). Age > 35 years old (AOR = 2.34, 95%CI, 1.74-2.94; p-value = 0.64), housewife (AOR = 2.76, 95%CI, 1.2-4.32; p-value = 0.37), previous history of pre-eclampsia (AOR = 4.02, 95%CI, 2.91-5.55; p-value = 0.09), family history of hypertension (OR = 1.84, 95%CI, 1.39-2.3; p-value = 0.4), history of chronic hypertension (AOR = 2.44, 95%CI, 1.8-3.08; p-value = 0.67), history of multiple pregnancies (AOR = 1.45, 95%CI, 1.09-1.8; p-value = 0.38), and alcohol intake during pregnancy (AOR = 1.53, 95%CI, 1.03-2.04; p-value = 0.03) were the determinants of pre-eclampsia.

CONCLUSIONS

When compared to previous studies, the overall pooled prevalence of pre-eclampsia was high. Pre-eclampsia is associated with maternal age >35 years, being a housewife, having a history of preeclampsia, having a history of chronic hypertension, having a family history of hypertension, having diabetes mellitus, drinking alcohol during pregnancy, and having multiple pregnancies.

摘要

背景

子痫前期是一种严重的疾病,与围产期不良结局有关。在埃塞俄比亚,子痫前期的总体患病率及其相关因素尚不确定。因此,本综述的目的是确定埃塞俄比亚子痫前期的患病率及其决定因素。

方法

为了找到原始研究,我们于 2013 年 1 月 1 日至 2023 年 1 月 1 日在埃塞俄比亚使用了 PubMed、Google Scholar、HINAR、Scopus、Web of Sciences 和灰色文献搜索。我们使用 Microsoft Excel 表格提取数据。使用随机效应模型预测子痫前期的汇总患病率。

结果

共纳入 29 项研究。子痫前期的汇总患病率为 11.51%(95%CI:8.41,14.61)。年龄>35 岁(AOR=2.34,95%CI,1.74-2.94;p 值=0.64)、家庭主妇(AOR=2.76,95%CI,1.2-4.32;p 值=0.37)、既往子痫前期病史(AOR=4.02,95%CI,2.91-5.55;p 值=0.09)、高血压家族史(OR=1.84,95%CI,1.39-2.3;p 值=0.4)、慢性高血压病史(AOR=2.44,95%CI,1.8-3.08;p 值=0.67)、多胎妊娠史(AOR=1.45,95%CI,1.09-1.8;p 值=0.38)和妊娠期饮酒(AOR=1.53,95%CI,1.03-2.04;p 值=0.03)是子痫前期的决定因素。

结论

与以往研究相比,子痫前期的总体汇总患病率较高。子痫前期与母亲年龄>35 岁、家庭主妇、子痫前期病史、慢性高血压病史、高血压家族史、糖尿病、妊娠期饮酒和多胎妊娠有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee1b/10645334/04e59adbc5ec/pone.0287038.g010.jpg
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