Department of Food Science & Technology, School of Agriculture and Biology, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang District, Shanghai 200240, China.
Yunnan Dali Research Institute of Shanghai Jiao Tong University, Yunnan 671000, China.
Anal Methods. 2023 Nov 30;15(46):6320-6343. doi: 10.1039/d3ay01815f.
Heavy metal ion contamination poses significant environmental and health risks, necessitating rapid and efficient detection methods. In the last decade, colorimetric aptasensors have emerged as powerful tools for heavy metal ion detection, owing to their notable attributes such as high specificity, facile synthesis, adaptability to modifications, long-term stability, and heightened sensitivity. This comprehensive overview summarizes the key developments in this field over the past ten years. It discusses the principles, design strategies, and innovative techniques employed in colorimetric aptasensors using nanomaterials. Recent advancements in enhancing sensitivity, selectivity, and on-site applicability are highlighted. The review also presents application studies of successful heavy metal ion detection using colorimetric aptasensors, underlining their potential for environmental monitoring and health protection. Finally, future directions and challenges in the continued evolution of these aptasensors are outlined.
重金属离子污染对环境和健康构成重大风险，因此需要快速高效的检测方法。在过去十年中，比色适体传感器作为重金属离子检测的有力工具而出现，这归因于它们具有高特异性、易于合成、可适性修饰、长期稳定性和高灵敏度等显著特点。本综述总结了过去十年中该领域的主要发展。它讨论了使用纳米材料的比色适体传感器的原理、设计策略和创新技术。强调了提高灵敏度、选择性和现场适用性的最新进展。该综述还介绍了成功使用比色适体传感器进行重金属离子检测的应用研究，突出了它们在环境监测和健康保护方面的潜力。最后，概述了这些适体传感器不断发展所面临的未来方向和挑战。
