Photothermal Conversion Efficiency of Silver and Gold Incorporated Nanosized Apatites for Biomedical Applications.

The aim of this research was to investigate the photothermal ability of nanocrystalline hydroxyapatite (nHAp) incorporated with silver and gold. It was studied by using a recently developed technique evaluating the photothermal conversion efficiency. The heating performance of aqueous dispersions was examined under 445 and 532 nm excitation. The largest increase in temperature was found for the 2% Ag-nHAp and reached above 2 °C per mg/mL of sample (445 nm) under 90 mW laser continuous irradiation and an external light-to-heat conversion efficiency of 0.11 L/g cm. The obtained results have shown a new functionality of nanosized apatites that has not been considered before. The studied materials have also been characterized by XRPD, TEM, BET, and UV-Vis techniques. Finally, in this work, a new idea for their application was proposed: photothermal therapy.