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MetaboLights:代谢组学开放数据知识库。

MetaboLights: open data repository for metabolomics.

机构信息

European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

出版信息

Nucleic Acids Res. 2024 Jan 5;52(D1):D640-D646. doi: 10.1093/nar/gkad1045.

Abstract

MetaboLights is a global database for metabolomics studies including the raw experimental data and the associated metadata. The database is cross-species and cross-technique and covers metabolite structures and their reference spectra as well as their biological roles and locations where available. MetaboLights is the recommended metabolomics repository for a number of leading journals and ELIXIR, the European infrastructure for life science information. In this article, we describe the continued growth and diversity of submissions and the significant developments in recent years. In particular, we highlight MetaboLights Labs, our new Galaxy Project instance with repository-scale standardized workflows, and how data public on MetaboLights are being reused by the community. Metabolomics resources and data are available under the EMBL-EBI's Terms of Use at https://www.ebi.ac.uk/metabolights and under Apache 2.0 at https://github.com/EBI-Metabolights.

摘要

代谢组学文献数据库(MetaboLights)是一个全球性的数据库,包含代谢组学研究的原始实验数据和相关元数据。该数据库具有跨物种和跨技术的特点,涵盖了代谢物结构及其参考光谱,以及它们的生物学作用和可用的位置。MetaboLights 是许多领先期刊和 ELIXIR(欧洲生命科学信息基础设施)推荐的代谢组学存储库。在本文中,我们描述了持续增长和多样性的提交内容,以及近年来的重大发展。特别是,我们强调了 MetaboLights Labs,我们的新 Galaxy 项目实例,具有存储库规模的标准化工作流程,以及社区如何重用 MetaboLights 上公开的数据。代谢组学资源和数据可在 EMBL-EBI 的使用条款下获得,网址为 https://www.ebi.ac.uk/metabolights,也可在 Apache 2.0 许可下获得,网址为 https://github.com/EBI-Metabolights。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/090d/10767962/3c9a009d82ec/gkad1045figgra1.jpg

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