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代谢组学文献共享资源库(MetaboLights):一个响应其科研群体需求而不断发展的资源库。

MetaboLights: a resource evolving in response to the needs of its scientific community.

机构信息

European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

出版信息

Nucleic Acids Res. 2020 Jan 8;48(D1):D440-D444. doi: 10.1093/nar/gkz1019.

Abstract

MetaboLights is a database for metabolomics studies, their raw experimental data and associated metadata. The database is cross-species and cross-technique and it covers metabolite structures and their reference spectra as well as their biological roles and locations. MetaboLights is the recommended metabolomics repository for a number of leading journals and ELIXIR, the European infrastructure for life science information. In this article, we describe the significant updates that we have made over the last two years to the resource to respond to the increasing amount and diversity of data being submitted by the metabolomics community. We refreshed the website and most importantly, our submission process was completely overhauled to enable us to deliver a far more user-friendly submission process and to facilitate the growing demand for reproducibility and integration with other 'omics. Metabolomics resources and data are available under the EMBL-EBI's Terms of Use via the web at https://www.ebi.ac.uk/metabolights and under Apache 2.0 at Github (https://github.com/EBI-Metabolights/).

摘要

MetaboLights 是一个用于代谢组学研究的数据库,其中包含原始实验数据和相关元数据。该数据库具有跨物种和跨技术的特点,涵盖了代谢物结构及其参考光谱,以及它们的生物学作用和位置。MetaboLights 是许多领先期刊和 ELIXIR(欧洲生命科学信息基础设施)推荐的代谢组学存储库。在本文中,我们将介绍过去两年中我们对该资源进行的重大更新,以应对代谢组学社区提交的数据量和多样性不断增加的情况。我们更新了网站,最重要的是,我们的提交流程进行了全面改革,使我们能够提供更用户友好的提交流程,并促进对可重复性和与其他“组学”集成的需求的增长。代谢组学资源和数据可根据 EMBL-EBI 的使用条款通过网络在 https://www.ebi.ac.uk/metabolights 上获得,并可根据 Apache 2.0 在 Github(https://github.com/EBI-Metabolights/)上获得。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/796e/7145518/daa68c2fbdf2/gkz1019fig1.jpg

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