Wellcome Trust Genome Campus, European Bioinformatics Institute, Cheminformatics and Metabolism, Hinxton, Cambridgeshire CB10 1SD, UK.
Database (Oxford). 2013 Apr 29;2013:bat029. doi: 10.1093/database/bat029. Print 2013.
MetaboLights is the first general-purpose open-access curated repository for metabolomic studies, their raw experimental data and associated metadata, maintained by one of the major open-access data providers in molecular biology. Increases in the number of depositions, number of samples per study and the file size of data submitted to MetaboLights present a challenge for the objective of ensuring high-quality and standardized data in the context of diverse metabolomic workflows and data representations. Here, we describe the MetaboLights curation pipeline, its challenges and its practical application in quality control of complex data depositions. Database URL: http://www.ebi.ac.uk/metabolights.
MetaboLights 是第一个通用的开放获取代谢组学研究、原始实验数据和相关元数据的精选知识库，由分子生物学领域的主要开放获取数据提供商之一维护。代谢组学研究中提交的数据数量、每个研究的样本数量和文件大小的增加，给确保在多样化的代谢组学工作流程和数据表示背景下数据的高质量和标准化带来了挑战。在这里，我们描述了 MetaboLights 精选知识库的管理流程、其挑战以及在复杂数据提交的质量控制中的实际应用。数据库 URL：http://www.ebi.ac.uk/metabolights。
