Steinbeck Christoph, Conesa Pablo, Haug Kenneth, Mahendraker Tejasvi, Williams Mark, Maguire Eamonn, Rocca-Serra Philippe, Sansone Susanna-Assunta, Salek Reza M, Griffin Julian L
European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD UK.
Metabolomics. 2012 Oct;8(5):757-760. doi: 10.1007/s11306-012-0462-0. Epub 2012 Sep 25.
Exciting funding initiatives are emerging in Europe and the US for metabolomics data production, storage, dissemination and analysis. This is based on a rich ecosystem of resources around the world, which has been build during the past ten years, including but not limited to resources such as MassBank in Japan and the Human Metabolome Database in Canada. Now, the European Bioinformatics Institute has launched MetaboLights, a database for metabolomics experiments and the associated metadata (http://www.ebi.ac.uk/metabolights). It is the first comprehensive, cross-species, cross-platform metabolomics database maintained by one of the major open access data providers in molecular biology. In October, the European COSMOS consortium will start its work on Metabolomics data standardization, publication and dissemination workflows. The NIH in the US is establishing 6-8 metabolomics services cores as well as a national metabolomics repository. This communication reports about MetaboLights as a new resource for Metabolomics research, summarises the related developments and outlines how they may consolidate the knowledge management in this third large omics field next to proteomics and genomics.
在欧洲和美国，针对代谢组学数据的生成、存储、传播及分析，令人振奋的资金支持计划正在涌现。这基于全球丰富的资源生态系统，该生态系统在过去十年间得以建立，其中包括但不限于日本的MassBank和加拿大的人类代谢组数据库等资源。如今，欧洲生物信息学研究所推出了MetaboLights，这是一个用于代谢组学实验及相关元数据的数据库（http://www.ebi.ac.uk/metabolights）。它是由分子生物学领域主要的开放获取数据提供商之一维护的首个全面、跨物种、跨平台的代谢组学数据库。10月，欧洲COSMOS联盟将启动代谢组学数据标准化、发布及传播工作流程的相关工作。美国国立卫生研究院正在建立6 - 8个代谢组学服务核心以及一个国家代谢组学知识库。本通讯报道了MetaboLights作为代谢组学研究的新资源，总结了相关进展，并概述了它们如何发展如何如何巩固这一仅次于蛋白质组学和基因组学的第三大组学领域的知识管理。
