Avery M E, Tooley W H, Keller J B, Hurd S S, Bryan M H, Cotton R B, Epstein M F, Fitzhardinge P M, Hansen C B, Hansen T N
Pediatrics. 1987 Jan;79(1):26-30.
Chronic lung disease in prematurely born infants, defined as the need for increased inspired oxygen at 28 days of age, was thought to be more common in some institutions than in others. To test this hypothesis, we surveyed the experience in the intensive care nurseries at Columbia and Vanderbilt Universities, the Universities of Texas at Dallas, Washington at Seattle, and California at San Francisco, the Brigham and Women's Hospital in Boston, Texas Children's Hospital in Houston, and Mt Sinai Hospital in Toronto. The survey included 1,625 infants with birth weights of 700 to 1,500 g. We confirmed the relationship of risk to low birth weight, white race, and male sex. Significant differences in the incidence of chronic lung disease were found between institutions even when birth weight, race, and sex were taken into consideration through a multivariate logistic regression analysis. Columbia had one of the best outcomes for low birth weight infants and the lowest incidence of chronic lung disease.
早产婴儿慢性肺病定义为在28日龄时需要增加吸入氧气量，据认为在一些机构比其他机构更为常见。为验证这一假设，我们调查了哥伦比亚大学、范德比尔特大学、得克萨斯大学达拉斯分校、华盛顿大学西雅图分校、加利福尼亚大学旧金山分校、波士顿布里格姆妇女医院、休斯敦德克萨斯儿童医院和多伦多西奈山医院的重症监护病房的情况。该调查纳入了1625名出生体重在700至1500克之间的婴儿。我们证实了风险与低出生体重、白人种族和男性性别的关系。即使通过多变量逻辑回归分析考虑了出生体重、种族和性别因素，各机构之间慢性肺病的发病率仍存在显著差异。哥伦比亚大学对于低出生体重婴儿的治疗效果最佳，慢性肺病的发病率最低。
