Thapar M K, Young E J
Pediatr Infect Dis. 1986 Nov-Dec;5(6):640-3. doi: 10.1097/00006454-198611000-00008.
In 1983 an outbreak of human brucellosis caused by Brucella melitensis occurred among residents of a predominantly Hispanic neighborhood in Houston, TX. The source of the infections was traced to unpasteurized goats' milk cheese imported from Mexico. Nineteen of the 31 patients who contracted the disease were members of 5 families, which included 11 children ranging in age from 2 to 17 years. Infection was generally associated with protein complaints and a paucity of physical findings. Both immunoglobulin M and immunoglobulin G agglutinins were present in acute phase sera in the majority of patients, and low titers of immunoglobulin M antibodies remained in the sera of 43% who were retested 2 years later. Trimethoprim-sulfamethoxozole was highly effective in the treatment of children with brucellosis and was associated with no relapses.
1983年，德克萨斯州休斯顿一个以西班牙裔为主的社区居民中爆发了由羊种布鲁氏菌引起的人间布鲁氏菌病。感染源追溯到从墨西哥进口的未经巴氏消毒的山羊奶酪。31名患病患者中有19名是5个家庭的成员，其中包括11名年龄在2至17岁之间的儿童。感染通常与蛋白质相关症状和少量体征有关。大多数患者急性期血清中同时存在免疫球蛋白M和免疫球蛋白G凝集素，两年后重新检测时，43%的患者血清中仍存在低滴度的免疫球蛋白M抗体。甲氧苄啶-磺胺甲恶唑对布鲁氏菌病患儿治疗效果极佳，且无复发情况。
