Sabbaghian H, Nadim A
J Hyg (Lond). 1974 Oct;73(2):221-8. doi: 10.1017/s0022172400024050.
Studies on brucellosis were carried out to elucidate the epidemiology of the disease in Isfahan province, where Brucella melitensis is highly prevalent in animals and man. A positive milk ring test of 32% and 23% was found in unvaccinated goats and sheep respectively. Card and tube agglutination tests showed an infection rate of about 12% in sheep and goats and 42% in cattle. B. melitensis was isolated from 8% of 677 samples of fresh cheese examined.Of 1526 clinically suspected human cases, 476 showed laboratory evidence of brucellosis. Of these patients, 291 cases were from urban and 185 cases from rural areas. Cases from urban and rural areas were seen principally in the younger age groups. The median age of infection was 19.7 in urban and 15.7 in rural patients respectively. The infection was encountered mainly from April to August. This correlates with animal parturition and the greatest amount of sheep and goat milk production, which is introduced to the local market as fresh cheese. Raw dairy product consumption is the most probable way of Brucella transmission in urban patients. In rural areas, both dairy product consumption and contact with animals are sources of infection.
开展了关于布鲁氏菌病的研究，以阐明伊斯法罕省该疾病的流行病学情况，在该省，羊种布鲁氏菌在动物和人类中高度流行。未接种疫苗的山羊和绵羊的乳环试验阳性率分别为32%和23%。平板凝集试验和试管凝集试验显示，绵羊和山羊的感染率约为12%，牛的感染率为42%。从677份新鲜奶酪样本中的8%分离出了羊种布鲁氏菌。在1526例临床疑似人类病例中，476例有布鲁氏菌病的实验室证据。在这些患者中，291例来自城市，185例来自农村地区。城市和农村地区的病例主要出现在较年轻的年龄组。城市患者的感染中位年龄分别为19.7岁，农村患者为15.7岁。感染主要发生在4月至8月。这与动物分娩以及绵羊和山羊奶产量最高的时期相关，这些羊奶作为新鲜奶酪进入当地市场。食用生鲜乳制品是城市患者感染布鲁氏菌最可能的途径。在农村地区，食用乳制品和与动物接触都是感染源。
