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人类感染羊布鲁氏菌病:一次因接触受感染山羊引发的疫情。

Human infection by Brucella melitensis: an outbreak attributed to contact with infected goats.

作者信息

Wallach J C, Samartino L E, Efron A, Baldi P C

机构信息

Sección Brucelosis, Hospital F.J. Muñiz, Buenos Aires, Argentina.

出版信息

FEMS Immunol Med Microbiol. 1997 Dec;19(4):315-21. doi: 10.1111/j.1574-695X.1997.tb01102.x.

DOI:10.1111/j.1574-695X.1997.tb01102.x
PMID:9537757
Abstract

Although several outbreaks of Brucella melitensis infection have been reported among laboratory workers or goat cheese consumers, outbreaks related to rural labour have been rarely studied. An outbreak of human brucellosis among farm workers of Argentina was studied and revealed a close relationship with an epidemic of caprine abortions which occurred shortly before on the same farm. High rates of B. melitensis infection were found among goats. Active brucellosis was diagnosed in 33 subjects (14 with positive blood culture for B. melitensis), while other 27 did not show evidence of illness. While 25 of the brucellosis active patients were rural workers, only 5 of the healthy subjects were engaged in rural labour. Active brucellosis was diagnosed in 91.3% of the subjects in continuous contact with goats and in 32% of those having an occasional contact with the animals. All the 60 subjects denied consumption of goat cheese or milk. As shown here, epidemic human infections by B. melitensis may develop among people frequently in contact with infected goat herds or goat manure.

摘要

尽管已有多起关于实验室工作人员或山羊奶酪消费者感染布鲁氏菌病的报道,但与农村劳动力相关的疫情却鲜有研究。对阿根廷农场工人中发生的一起人类布鲁氏菌病疫情进行了研究,结果显示其与同一农场此前不久发生的山羊流产疫情密切相关。在山羊中发现了高感染率的羊种布鲁氏菌。33名受试者被诊断为活动性布鲁氏菌病(14人血培养出羊种布鲁氏菌呈阳性),而另外27人未显示出患病迹象。活动性布鲁氏菌病患者中有25人是农村工人,而健康受试者中只有5人从事农村劳动。与山羊持续接触的受试者中91.3%被诊断为活动性布鲁氏菌病,偶尔接触动物的受试者中这一比例为32%。所有60名受试者均否认食用过山羊奶酪或羊奶。如此处所示,羊种布鲁氏菌引起的人类流行性感染可能在经常接触受感染山羊群或山羊粪便的人群中发生。

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