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气候变化、暴露组变化与过敏:综述

Climate Change, Exposome Change, and Allergy: A Review.

机构信息

Department of Environmental Medicine and Public Health, Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl, New York, NY 10029, USA.

Department of Dermatology, Besat Hospital, Kurdistan University of Medical Sciences, Sanandaj, Iran.

出版信息

Immunol Allergy Clin North Am. 2024 Feb;44(1):1-13. doi: 10.1016/j.iac.2023.09.003. Epub 2023 Oct 14.

Abstract

Climate change is a major threat to human respiratory health and associated allergic disorders given its broad impact on the exposome. Climate change can affect exposure to allergens, such as pollen, dust mites, molds, as well as other factors such as temperature, air pollution, and nutritional factors, which synergistically impact the immune response to these allergens. Exposome change can differentially exacerbate allergic reactions across subgroups of populations, especially those who are more vulnerable to environmental stressors. Understanding links between climate change and health impacts can help inform how to protect individuals and vulnerable populations from adverse health effects.

摘要

气候变化是人类呼吸健康和相关过敏疾病的主要威胁,因为它对暴露组有广泛的影响。气候变化会影响过敏原的暴露,如花粉、尘螨、霉菌,以及其他因素,如温度、空气污染和营养因素,这些因素协同影响对这些过敏原的免疫反应。暴露组的变化会使不同亚组人群的过敏反应恶化,尤其是那些更容易受到环境压力的人群。了解气候变化与健康影响之间的联系可以帮助我们了解如何保护个人和弱势群体免受不良健康影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ecf/11000425/b1970de36903/nihms-1980312-f0001.jpg

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