Division of General Pediatrics, Departments of Pediatrics and Environmental Medicine & Public Health, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1198, New York, NY 10029, USA.
Immunol Allergy Clin North Am. 2024 Feb;44(1):85-96. doi: 10.1016/j.iac.2023.09.002.
Asthma and allergic disorders are common in childhood with genetic and environmental determinants of disease that include prenatal nutritional exposures such as long-chain polyunsaturated fatty acids and antioxidants. Global climate change is implicated in asthma and allergic disorder morbidity with potential mechanisms including perturbations of ecosystems. There is support that environmental and climatic changes such as increasing global temperate and carbon dioxide levels affect aquatic and agricultural ecosystems with subsequent alterations in long-chain polyunsaturated fatty acid availability and nutrient quality and antioxidant capacity of certain crops, respectively. This article discusses asthma epidemiology and the influence of global climate change.
哮喘和过敏性疾病在儿童中很常见，其发病的遗传和环境决定因素包括长链多不饱和脂肪酸和抗氧化剂等产前营养暴露。全球气候变化与哮喘和过敏性疾病的发病率有关，其潜在机制包括生态系统的紊乱。有证据表明，环境和气候变化，如全球温度升高和二氧化碳水平升高，会影响水生和农业生态系统，从而导致长链多不饱和脂肪酸的供应以及某些农作物的营养质量和抗氧化能力发生变化。本文讨论了哮喘的流行病学以及全球气候变化的影响。
