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表现为 IgG4 相关鼻部肿块的鼻腔鼻窦神经鞘瘤。

Sinonasal schwannoma masquerading as an IgG4-related nasal mass.

机构信息

Otorhinolaryngology and Head and Neck Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Grewal Eye Institute, Chandigarh, Chandigarh, India.

出版信息

BMJ Case Rep. 2023 Nov 16;16(11):e255135. doi: 10.1136/bcr-2023-255135.

DOI:10.1136/bcr-2023-255135
PMID:37973538
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10660653/
Abstract

An elderly (8th decade) diabetic patient presented with insidious, painless protrusion of the right eye for 1 month, associated with nasal congestion. Past history included healed serous chorioretinopathy in the right eye (>30 years back) and recently diagnosed (1 year prior) autoimmune IgG4-related pancreatitis for which he was on long-term corticosteroids. On nasal endoscopic examination, a well circumscribed mass was found in the right nasal cavity.Keeping in mind the systemic diagnosis, the sinonasal mass was suspected to be a IgG4-related disease. An endoscopic biopsy was performed and revealed a surprise diagnosis of grade 1 nasal schwannoma.

摘要

一位 80 多岁的老年糖尿病患者,1 个月来出现右眼进行性、无痛性突出,伴有鼻塞。既往史包括右眼浆液性脉络膜视网膜病变(30 多年前)和最近诊断的自身免疫 IgG4 相关胰腺炎(1 年前),为此他长期服用皮质类固醇。鼻内镜检查发现右侧鼻腔有一个界限清楚的肿块。考虑到全身诊断,鼻窦肿块疑为 IgG4 相关疾病。进行了内镜活检,结果出乎意料地诊断为 1 级鼻腔神经鞘瘤。

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本文引用的文献

1
Sinonasal IgG4-related sclerosing disease: A rare entity and challenging diagnosis.鼻窦IgG4相关性硬化性疾病:一种罕见且诊断具有挑战性的疾病。
Laryngoscope Investig Otolaryngol. 2022 Oct 11;7(6):1725-1732. doi: 10.1002/lio2.944. eCollection 2022 Dec.
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An Extensive Unilateral Nasal Mass: Septal Schwannoma-Case Report.一例广泛的单侧鼻腔肿物:鼻中隔施万细胞瘤——病例报告
Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):1540-1543. doi: 10.1007/s12070-021-02635-4. Epub 2021 Jun 10.
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Imaging of IgG4-related disease in the extracranial head and neck.IgG4 相关疾病的颅外头颈部影像学表现。
Eur J Radiol. 2021 Mar;136:109560. doi: 10.1016/j.ejrad.2021.109560. Epub 2021 Jan 27.
4
Sinonasal IgG4-related disease: a rare and emerging entity broadening the differential diagnosis in the sinonasal universe.鼻窦 IgG4 相关疾病:一种罕见且新兴的疾病实体,拓宽了鼻窦领域的鉴别诊断范围。
Eur Arch Otorhinolaryngol. 2021 Aug;278(8):2883-2890. doi: 10.1007/s00405-020-06564-w. Epub 2021 Jan 4.
5
Immunoglobulin G4-related disease of the paranasal sinuses.鼻窦的免疫球蛋白G4相关性疾病。
BMJ Case Rep. 2018 May 7;2018:bcr-2018-224472. doi: 10.1136/bcr-2018-224472.
6
Frontal sinus schwannoma.额窦神经鞘瘤。
Eur Ann Otorhinolaryngol Head Neck Dis. 2018 Jun;135(3):213-215. doi: 10.1016/j.anorl.2018.03.001. Epub 2018 Apr 25.
7
CT and MR imaging findings of sinonasal schwannoma: a review of 12 cases.鼻窦神经鞘瘤的 CT 和 MRI 影像学表现:12 例病例回顾
AJNR Am J Neuroradiol. 2013 Mar;34(3):628-33. doi: 10.3174/ajnr.A3257. Epub 2012 Sep 6.
8
Clinico-pathological profile of sinonasal masses: a study from a tertiary care hospital of India.鼻窦肿块的临床病理特征:印度一家三级护理医院的研究。
Acta Otorhinolaryngol Ital. 2011 Dec;31(6):372-7.
9
CT and MR imaging findings in sinonasal schwannoma.鼻窦神经鞘瘤的CT和MR成像表现
AJNR Am J Neuroradiol. 2006 Apr;27(4):929-30.
10
Ethmoid schwannoma.筛窦神经鞘瘤。
Otolaryngol Head Neck Surg. 2005 Feb;132(2):334-5. doi: 10.1016/j.otohns.2004.04.027.