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肥胖患者的胃排空时间并不延长。

Gastric emptying is not prolonged in obese patients.

机构信息

Department of Surgery C, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.

出版信息

Surg Obes Relat Dis. 2013 Sep-Oct;9(5):714-7. doi: 10.1016/j.soard.2012.03.008. Epub 2012 Apr 3.

Abstract

BACKGROUND

Obesity is associated with a poor anesthetic risk, in part because of the greater aspiration rates. A greater gastric residue and lower stomach pH have been implicated. The relationship of obesity to gastric emptying is ill-defined. with contradicting reports stating shorter, similar, and longer times compared with nonobese subjects. The aim of the present study was to compare gastric emptying in obese and nonobese subjects at a university hospital.

METHODS

A total of 19 obese (body mass index [BMI] >40 kg/m(2)) and 20 nonobese (BMI <30 kg/m(2)) subjects underwent a standardized scintigraphic gastric emptying study. The participants consumed a standard semisolid, technetium-99m-labeled meal. Images were acquired immediately and 1, 2, and 4 hours after meal completion. The interval to evacuate one half of the counts measured at meal completion) and retention (the percentage of counts in stomach at each measurement point) were recorded.

RESULTS

The mean age and BMI was 35 years and 45 kg/m(2) in the obese and 44 years and 26 kg/m(2) in the nonobese group, respectively. No differences were found between the 2 groups regarding gastric emptying. Regression analysis showed no statistical association between the BMI and gastric emptying, including multivariate analysis, considering BMI, age, and gender.

CONCLUSION

A scintigraphy test of a labeled meal was used to evaluate gastric emptying in obese and nonobese subjects. In accordance with other published data, no significant difference was found between the 2 groups. The anesthetic risks in the obese should be attributed to factors other than delayed gastric emptying (i.e., anatomic variation, increased rates of hiatal hernia and reflux).

摘要

背景

肥胖与较差的麻醉风险相关,部分原因是由于更高的误吸率。人们认为胃内残留物更多和更低的胃 pH 值与此相关。肥胖与胃排空之间的关系尚未明确,有报道称肥胖者的胃排空时间比非肥胖者更短、相似或更长。本研究旨在比较肥胖和非肥胖患者在大学医院的胃排空情况。

方法

共有 19 名肥胖者(BMI>40kg/m²)和 20 名非肥胖者(BMI<30kg/m²)接受了标准化闪烁照相胃排空研究。参与者摄入了标准的半固体、锝-99m 标记的膳食。在进食完成后立即和 1、2 和 4 小时采集图像。记录排空一半计数的时间(即从进食完成时测量的计数中排空一半的时间间隔)和保留(每个测量点的胃内计数百分比)。

结果

肥胖组的平均年龄和 BMI 为 35 岁和 45kg/m²,非肥胖组分别为 44 岁和 26kg/m²。两组之间的胃排空情况无差异。回归分析显示,BMI 与胃排空之间无统计学关联,包括考虑 BMI、年龄和性别进行的多元分析。

结论

使用标记膳食闪烁照相术评估肥胖和非肥胖者的胃排空情况。与其他已发表的数据一致,两组之间未发现显著差异。肥胖者的麻醉风险不应归因于胃排空延迟(即解剖变异、食管裂孔疝和反流的发生率增加)等因素。

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