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用于人类疼痛研究的牙科痛觉测量法:方法与仪器

Dental dolorimetry for human pain research: methods and apparatus.

作者信息

Martin Roy W, Chapman Richard C

机构信息

Departments of Anesthesiology, Psychiatry and Behavioral Sciences and Psychology, University of Washington, Seattle, Wash. 98195 U.S.A.

出版信息

Pain. 1979 Jun;6(3):349-364. doi: 10.1016/0304-3959(79)90053-8.

DOI:10.1016/0304-3959(79)90053-8
PMID:379748
Abstract

Electrical stimulation of human tooth pulp provides a means of safely producing human pain in the laboratory. This paper describes a dolorimetry and data collection system for stimulating volunteers, recording responses and analyzing data. The system allows multilevel stimulation in pseudorandom sequences and analysis of results using the methods of Sensory Decision Theory. It consists of modified commercial equipment, specially designed circuitry, an interface, and a programmable calculator. Fundamental problems and safety considerations for electrical dental stimulation are reviewed. Reliability of stimulation and response measurement is discussed.

摘要

对人类牙髓进行电刺激为在实验室中安全诱发人体疼痛提供了一种方法。本文描述了一种用于刺激志愿者、记录反应并分析数据的痛觉测量与数据收集系统。该系统允许以伪随机序列进行多级刺激,并使用感觉决策理论方法对结果进行分析。它由改良的商用设备、专门设计的电路、一个接口和一台可编程计算器组成。本文回顾了牙科电刺激的基本问题和安全注意事项。还讨论了刺激和反应测量的可靠性。

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1
Dental dolorimetry for human pain research: methods and apparatus.用于人类疼痛研究的牙科痛觉测量法:方法与仪器
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Pulpal ischemia in man: effects on detection threshold, A-delta neural response and sharp dental pain.
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Systemic administration of lidocaine suppresses the excitability of rat cervical dorsal horn neurons and tooth-pulp-evoked jaw-opening reflex.利多卡因的全身给药抑制大鼠颈背角神经元的兴奋性以及牙髓诱发的下颌张开反射。
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The paradox of pain from tooth pulp: low-threshold "algoneurons"?牙髓疼痛的悖论:低阈值“痛觉神经元”?
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Acute experimental dental pain: a technique for evaluating pain modulating procedures.急性实验性牙痛:一种评估疼痛调节程序的技术。
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Meta-analysis on brain representation of experimental dental pain.实验性牙痛的大脑表象的荟萃分析。
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Differential effects of noxious conditioning stimulation of the cheek by capsaicin on human sensory and inhibitory masseter reflex responses evoked by tooth pulp stimulation.辣椒素对脸颊进行有害条件刺激对牙髓刺激诱发的人类感觉性和抑制性咬肌反射反应的不同影响。
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The mechanisms of pain from dentine and pulp.来自牙本质和牙髓的疼痛机制。
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Measurement of pain threshold by electrical stimulation of tooth pulp afferents in the monkey.通过电刺激猴子牙髓传入神经来测量疼痛阈值。
Exp Neurol. 1978 Sep 1;61(2):260-9. doi: 10.1016/0014-4886(78)90245-5.
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Encoding of the subjective intensity of sharp dental pain.尖锐牙痛主观强度的编码。
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引用本文的文献

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Electroencephalography and analgesics.脑电图与镇痛药。
Br J Clin Pharmacol. 2014 Jan;77(1):72-95. doi: 10.1111/bcp.12137.
2
Rate of stimulus repetition changes evoked potential amplitude: dental and auditory modalities compared.
Exp Brain Res. 1981;43(3-4):246-52. doi: 10.1007/BF00238365.
3
Reactions to pain among subjects high and low in dental fear.
J Behav Med. 1980 Dec;3(4):373-84. doi: 10.1007/BF00845291.
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Analgesic action of intravenous diazepam.
静脉注射地西泮的镇痛作用。
Anesth Prog. 1984 Mar-Apr;31(2):70-3.
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Opiate analgesia and its antagonism in dental event-related potentials: evidence for placebo antagonism.
Psychopharmacology (Berl). 1983;79(4):325-8. doi: 10.1007/BF00433411.