Bini G, Cruccu G, Manfredi M
J Neurosci Methods. 1981 Feb;3(3):301-9. doi: 10.1016/0165-0270(81)90066-2.
A simple method for bipolar electrical stimulation of the tooth pulp for evaluating pain modulating procedures is described. Stimulation selectivity has been studied by means of cortical evoked potentials before and after gum anaesthesia. Results obtained by constant current and constant voltage stimulation have been compared. Constant voltage stimulation has proved to be more stable in time. This technique is able to differentiate the analgesic effect of a single dose of i.v. lysine acetylsalicylate from saline. Threshold sensation was judged as painful by about half of the subjects.
本文描述了一种用于评估疼痛调节程序的牙髓双极电刺激简单方法。通过牙龈麻醉前后的皮层诱发电位研究了刺激选择性。比较了恒流刺激和恒压刺激获得的结果。结果表明恒压刺激在时间上更稳定。该技术能够区分单次静脉注射赖氨酸乙酰水杨酸酯和生理盐水的镇痛效果。约一半受试者将阈感觉判定为疼痛。