Dean Jordan, McTavish Sloane, Feng Yilin, Hoyek Sandra, Patel Nimesh A
University of Connecticut School of Medicine, Farmington, CT, USA.
University of Virginia School of Medicine, Charlottesville, VA, USA.
J Vitreoretin Dis. 2023 May 24;7(6):557-561. doi: 10.1177/24741264231176143. eCollection 2023 Nov-Dec.
To report 2 cases of persistent inflammation associated with human leukocyte antigen-B27 (HLA-B27) after pars plana vitrectomy (PPV) with scleral buckling. Two cases were analyzed. A 47-year-old man had pars plana vitrectomy (PPV), scleral buckle (SB) placement, and endolaser for a macula-on rhegmatogenous retinal detachment (RRD). A 61-year-old man also had uneventful PPV, SB placement, and endolaser for a macula-off RRD. Postoperatively, both patients reported eye pain and had persistent intraocular inflammation. Both were found to be HLA-B27 positive despite having no previous signs or symptoms that would warrant HLA-B27 testing. Discovering the source of prolonged postoperative inflammation is critical in initiating the correct treatment and removing suspicion of infection. Although intraocular inflammation associated with HLA-B27 does not often present initially after surgery, HLA-B27 testing should be considered in cases of persistent, unexpected postoperative inflammation.
报告2例在巩膜扣带术联合玻璃体切割术后出现与人类白细胞抗原B27（HLA - B27）相关的持续性炎症的病例。对2例病例进行了分析。一名47岁男性因黄斑在位的孔源性视网膜脱离接受了玻璃体切割术（PPV）、巩膜扣带术（SB）及眼内激光光凝治疗。一名61岁男性也因黄斑不在位的孔源性视网膜脱离顺利接受了PPV、SB及眼内激光光凝治疗。术后，两名患者均诉眼痛且存在持续性眼内炎症。尽管此前没有任何体征或症状表明需要进行HLA - B27检测，但两人均被发现HLA - B27呈阳性。查明术后长期炎症的来源对于启动正确治疗及消除感染疑虑至关重要。虽然与HLA - B27相关的眼内炎症在术后最初并不常出现，但对于持续性、意外的术后炎症病例，应考虑进行HLA - B27检测。
