Bondar' I A, Khudonogova Z P
Ter Arkh. 1986;58(10):88-91.
Examination of the interferon response of leukocytes in 119 patients with diabetes mellitus has demonstrated that interferon formation is influenced by a lot of factors. During counterbalancing of the metabolic disorders interferon formation was increased, being attended by marked clinical improvement of the patients. In the course of the treatment there was no rise in interferon production if the disease progressed rapidly and was accompanied by grave illnesses. The interferon response of leukocytes mirrors the gravity of metabolic abnormalities and can be used as an important prognostic test in the evaluation of the course of diabetes mellitus.
对119例糖尿病患者白细胞的干扰素反应进行检测后发现，干扰素的形成受多种因素影响。在代谢紊乱得到平衡的过程中，干扰素的形成增加，同时患者的临床症状明显改善。在治疗过程中，如果疾病进展迅速且伴有严重疾病，干扰素的产生不会增加。白细胞的干扰素反应反映了代谢异常的严重程度，可作为评估糖尿病病情的一项重要预后指标。
