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非小细胞肺癌患者心电图变化的近期死亡预警价值。

Recent death early warning value of ECG changes in patients with NSCLC.

机构信息

Department of ECG Room, Chaohu Hospital affiliated to Anhui Medical University, Chaohu City, Hefei City, Anhui Province, China.

Department of ECG Function, Zhejiang Provincial People's Hospital, Hangzhou City, Zhejiang Province, China.

出版信息

Medicine (Baltimore). 2023 Nov 17;102(46):e35698. doi: 10.1097/MD.0000000000035698.

DOI:10.1097/MD.0000000000035698
PMID:37986366
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10659719/
Abstract

We aimed to explore the predictive value of abnormal electrocardiogram (ECG) changes in non-small-cell lung carcinoma non-small cell lung cancer (NSCLC) patients for near-term mortality. Seventy-eight NSCLC patients hospitalized in Chaohu Hospital Affiliated to Anhui Medical University from October 2017 to August 2021 were selected as the observation group. Baseline medical history and type of ECG abnormalities were the same. Seventy-eight patients were included in the control group. To compare the difference in mortality within 3 months between the observation group and the control group after the occurrence of the same type of electrocardiogram abnormalities, and to explore the value of electrocardiogram abnormalities in the early warning of NSCLC patients recent death. When the average ventricular rate of patients in the observation group was ≥100 beats/minute, ST-segment depression ≥0.05 mm, QRS voltage decrease ≥0.5 mm, new atrial fibrillation and other electrocardiogram changes, all patients died within 3 months. The control group with the same abnormal ECG had no death within 3 months (P < .05). In the resting 12-lead synchronous ECG in NSCLC patients, when the average ventricular rate ≥100 beats/minute, QRS wave voltage significantly decreased ≥0.5 mm, ST segment depression ≥0.05 mm, new atrial fibrillation appeared, it suggested that the patients' cardiac function decreased and the potential for near-term adverse outcomes is high.

摘要

我们旨在探讨非小细胞肺癌(NSCLC)患者异常心电图(ECG)变化对近期死亡率的预测价值。选取 2017 年 10 月至 2021 年 8 月在安徽医科大学附属巢湖医院住院的 78 例 NSCLC 患者为观察组,两组基线病史及 ECG 异常类型相同。另选取同期 78 例 ECG 异常类型相同的患者为对照组。比较观察组与对照组相同类型 ECG 异常后 3 个月内死亡率的差异,探讨心电图异常对 NSCLC 患者近期死亡的预警价值。当观察组患者平均心室率≥100 次/分时,ST 段压低≥0.05mm,QRS 波电压降低≥0.5mm,出现新发心房颤动等心电图改变时,所有患者均在 3 个月内死亡。同期对照组出现相同异常 ECG 但无死亡(P<.05)。在 NSCLC 患者静息 12 导联同步心电图中,当平均心室率≥100 次/分时,QRS 波电压显著降低≥0.5mm,ST 段压低≥0.05mm,出现新发心房颤动时,提示患者心功能下降,近期发生不良结局的潜在风险较高。

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