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基于大数据的应急临床科研集成平台构建

[Construction of integrated platform for emergency clinical scientific research based on big data].

作者信息

Zhu Gongxu, Li Yunmei, Chen Xiaohui, Li Yanling, Zhu Yongcheng, Mao Haifeng, Qu Zhenzhong, Li Kunlian, Wang Sai, Yang Guangqian, Lu Huijing, Jiang Huilin

机构信息

Department of Emergency, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, Guangdong, China.

Beijing Jiahe Hessian Health Technology Co., Ltd, Beijing 100007, China.

出版信息

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2023 Nov;35(11):1218-1222. doi: 10.3760/cma.j.cn121430-20230403-00240.

Abstract

OBJECTIVE

To explore clinical rules based on the big data of the emergency department of the Second Affiliated Hospital of Guangzhou Medical University, and to establish an integrated platform for clinical research in emergency, which was finally applied to clinical practice.

METHODS

Based on the hospital information system (HIS), laboratory information system (LIS), emergency specialty system, picture archiving and communication systems (PACS) and electronic medical record system of the Second Affiliated Hospital of Guangzhou Medical University, the structural and unstructured information of patients in the emergency department from March 2019 to April 2022 was extracted. By means of extraction and fusion, normalization and desensitization quality control, the database was established. In addition, data were extracted from the database for adult patients with pre screening triage level III and below who underwent emergency visits from March 2019 to April 2022, such as demographic characteristics, vital signs during pre screening triage, diagnosis and treatment characteristics, diagnosis and grading, time indicators, and outcome indicators, independent risk factors for poor prognosis in patients were analyzed.

RESULTS

(1) The data of 338 681 patients in the emergency department of the Second Affiliated Hospital of Guangzhou Medical University from March 2019 to April 2022 were extracted, including 15 modules, such as demographic information, triage information, visit information, green pass and rescue information, diagnosis information, medical record information, laboratory examination overview, laboratory information, examination information, microbiological information, medication information, treatment information, hospitalization information, chest pain management and stroke management. The database ensured data visualization and operability. (2) Total 140 868 patients with pre-examination and triage level III and below were recruited from the emergency department database. The gender, age, type of admission to the hospital, pulse, blood pressure, Glasgow coma scale (GCS) and other indicators of the patients were included. Taking emergency admission to operating room, emergency admission to intervention room, emergency admission to intensive care unit (ICU) or emergency death as poor prognosis, the poor prognosis prediction model for patients with pre-examination and triage level III and below was constructed. The receiver operator characteristic curve and forest map results showed that the model had good predictive efficiency and could be used in clinical practice to reduce the risk of insufficient emergency pre-examination and triage.

CONCLUSIONS

The establishment of high-quality clinical database based on big data in emergency department is conducive to mining the clinical value of big data, assisting clinical decision-making, and improving the quality of clinical diagnosis and treatment.

摘要

目的

基于广州医科大学附属第二医院急诊科大数据探索临床规律,建立急诊临床研究一体化平台,并最终应用于临床实践。

方法

基于广州医科大学附属第二医院的医院信息系统(HIS)、实验室信息系统(LIS)、急诊专科系统、图像存档与通信系统(PACS)及电子病历系统,提取2019年3月至2022年4月急诊科患者的结构化和非结构化信息。通过提取融合、标准化及脱敏质控等手段建立数据库。此外,从数据库中提取2019年3月至2022年4月急诊就诊的预检分诊III级及以下成年患者的数据,如人口学特征、预检分诊时生命体征、诊疗特征、诊断及分级、时间指标、结局指标等,分析患者预后不良的独立危险因素。

结果

(1)提取了广州医科大学附属第二医院急诊科2019年3月至2022年4月338681例患者的数据,涵盖人口学信息、分诊信息、就诊信息、绿色通道及抢救信息、诊断信息、病历信息、检验概况、检验信息、检查信息、微生物信息、用药信息、治疗信息、住院信息、胸痛管理及卒中管理等15个模块。该数据库确保了数据的可视化及可操作性。(2)从急诊数据库中纳入140868例预检分诊III级及以下患者,纳入患者的性别、年龄、入院类型、脉搏、血压、格拉斯哥昏迷量表(GCS)等指标。将急诊入手术室、急诊入介入室、急诊入重症监护病房(ICU)或急诊死亡作为预后不良,构建了预检分诊III级及以下患者的预后不良预测模型。受试者工作特征曲线及森林图结果显示该模型具有良好的预测效能,可用于临床实践以降低急诊预检分诊不足的风险。

结论

基于急诊大数据建立高质量临床数据库有利于挖掘大数据临床价值,辅助临床决策,提高临床诊疗质量。

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