Department of Cardiology and Angiology, Justus Liebig University Giessen, 35390, Giessen, Germany.
Adiphea GmbH, Werbach, Germany.
Eur J Appl Physiol. 2024 Apr;124(4):1239-1252. doi: 10.1007/s00421-023-05353-7. Epub 2023 Nov 21.
The systolic blood pressure/workload (SBP/MET) slope was recently reported to be a reliable parameter to identify an exaggerated blood pressure response (eBPR) in the normal population and in athletes. However, it is unclear whether an eBPR correlates with central blood pressure (CBP) and vascular function in elite athletes.
We examined 618 healthy male elite athletes (age 25.8 ± 5.1 years) of mixed sports with a standardized maximum exercise test. CBP and vascular function were measured non-invasively with a validated oscillometric device. The SBP/MET slope was calculated and the threshold for an eBPR was set at > 6.2 mmHg/MET. Two groups were defined according to ≤ 6.2 and > 6.2 mmHg/MET, and associations of CBP and vascular function with the SBP/MET slope were compared for each group.
Athletes with an eBPR (n = 180, 29%) displayed a significantly higher systolic CBP (102.9 ± 7.5 vs. 100 ± 7.7 mmHg, p = 0.001) but a lower absolute (295 ± 58 vs. 384 ± 68 W, p < 0.001) and relative workload (3.14 ± 0.54 vs. 4.27 ± 1.1 W/kg, p < 0.001) compared with athletes with a normal SBP/MET slope (n = 438, 71%). Systolic CBP was positively associated with the SBP/MET slope (r = 0.243, p < 0.001). In multiple logistic regression analyses, systolic CBP (odds ratio [OR] 1.099, 95% confidence interval [CI] 1.045-1.155, p < 0.001) and left atrial volume index (LAVI) (OR 1.282, CI 1.095-1.501, p = 0.002) were independent predictors of an eBPR.
Systolic CBP and LAVI were independent predictors of an eBPR. An eBPR was further associated with a lower performance level, highlighting the influence of vascular function on the BPR and performance of male elite athletes.
收缩压/工作量(SBP/MET)斜率最近被报道是一种可靠的参数,可以识别正常人群和运动员中的血压反应过度(eBPR)。然而,在精英运动员中,eBPR 是否与中心血压(CBP)和血管功能相关尚不清楚。
我们检查了 618 名年龄为 25.8±5.1 岁的混合运动的健康男性精英运动员,进行了标准化的最大运动测试。使用经过验证的振荡测量设备无创性地测量 CBP 和血管功能。计算 SBP/MET 斜率,并将 eBPR 的阈值设定为>6.2mmHg/MET。根据≤6.2 和 >6.2mmHg/MET 将两组定义,并比较每组中 CBP 和血管功能与 SBP/MET 斜率的相关性。
有 eBPR 的运动员(n=180,29%)的收缩压 CBP 明显更高(102.9±7.5 与 100±7.7mmHg,p=0.001),但绝对(295±58 与 384±68W,p<0.001)和相对工作量(3.14±0.54 与 4.27±1.1W/kg,p<0.001)较低。与 SBP/MET 斜率正常的运动员(n=438,71%)相比。收缩压 CBP 与 SBP/MET 斜率呈正相关(r=0.243,p<0.001)。在多变量逻辑回归分析中,收缩压 CBP(优势比[OR]1.099,95%置信区间[CI]1.045-1.155,p<0.001)和左心房容积指数(LAVI)(OR 1.282,CI 1.095-1.501,p=0.002)是 eBPR 的独立预测因素。
收缩压 CBP 和 LAVI 是 eBPR 的独立预测因素。eBPR 进一步与较低的运动表现水平相关,突出了血管功能对男性精英运动员的 BPR 和表现的影响。