Bauer Pascal, Kraushaar Lutz, Hoelscher Sophie, Weber Rebecca, Akdogan Ebru, Keranov Stanislav, Dörr Oliver, Nef Holger, Hamm Christian W, Most Astrid
Medizinische Klinik I- Kardiologie/Angiologie, Justus Liebig Universitat Giessen, Giessen, Germany.
Adiphea, Adiphea GmbH, Werbach, Germany.
Sports Med Int Open. 2021 Apr 19;5(2):E45-E52. doi: 10.1055/a-1400-1897. eCollection 2021 Mar.
Workload-indexed blood pressure response (wiBPR) to exercise has been shown to be superior to peak systolic blood pressure (SBP) in predicting mortality in healthy men. Thus far, however, markers of wiBPR have not been evaluated for athletes and the association with vascular function is unclear. We examined 95 male professional athletes (26±5 y) and 30 male controls (26±4 y). We assessed vascular functional parameters at rest and wiBPR with a graded bicycle ergometer test and compared values for athletes with those of controls. Athletes had a lower pulse wave velocity (6.4±0.9 vs. 7.2±1.5 m/s, p=0.001) compared to controls. SBP/Watt slope (0.34±0.13 vs. 0.44±0.12 mmHg/W), SBP/MET slope (6.2±1.8 vs. 7.85±1.8 mmHg/MET) and peak SBP/Watt ratio (0.61±0.12 vs. 0.95±0.17 mmHg/W) were lower in athletes than in controls (p<0.001). The SBP/Watt and SBP/MET slope in athletes were comparable to the reference values, whereas the peak SBP/Watt-ratio was lower. All vascular functional parameters measured were not significantly correlated to the wiBPR in either athletes or controls. In conclusion, our findings indicate the potential use of the SBP/Watt and SBP/MET slope in pre-participation screening of athletes. Further, vascular functional parameters, measured at rest, were unrelated to the wiBPR in athletes and controls.
在预测健康男性的死亡率方面,运动负荷指数血压反应(wiBPR)已被证明优于收缩压峰值(SBP)。然而,迄今为止,尚未对运动员的wiBPR标志物进行评估,其与血管功能的关联也尚不清楚。我们研究了95名男性职业运动员(26±5岁)和30名男性对照组(26±4岁)。我们通过分级自行车测力计测试评估了静息时的血管功能参数和wiBPR,并将运动员的值与对照组进行了比较。与对照组相比,运动员的脉搏波速度较低(6.4±0.9对7.2±1.5米/秒,p = 0.001)。运动员的SBP/瓦特斜率(0.34±0.13对0.44±0.12mmHg/瓦特)、SBP/代谢当量斜率(6.2±1.8对7.85±1.8mmHg/代谢当量)和SBP峰值/瓦特比值(0.61±0.12对0.95±0.17mmHg/瓦特)均低于对照组(p<0.001)。运动员的SBP/瓦特和SBP/代谢当量斜率与参考值相当,而SBP峰值/瓦特比值较低。在运动员或对照组中,所测量的所有血管功能参数与wiBPR均无显著相关性。总之,我们的研究结果表明,SBP/瓦特和SBP/代谢当量斜率在运动员参赛前筛查中具有潜在用途。此外,静息时测量的血管功能参数与运动员和对照组的wiBPR无关。