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Comment on: The fragility index of randomized controlled trials in pediatric anesthesiology.

作者信息

Ho Anthony M-H, Sehgal Anupam, Leitch Jordan, Saha Tarit, Mizubuti Glenio B

机构信息

Department of Anesthesiology and Perioperative Medicine, Queen's University, Kingston, ON, Canada.

Department of Pediatrics, Kingston General Hospital, Queen's University, Kingston, ON, Canada.

出版信息

Can J Anaesth. 2024 Jan;71(1):163-164. doi: 10.1007/s12630-023-02658-1. Epub 2023 Nov 21.

DOI:10.1007/s12630-023-02658-1
PMID:37989936
Abstract
摘要

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Lowering the statistical significance threshold of randomized controlled trials in three major general anesthesiology journals.降低三大普通麻醉学期刊随机对照试验的统计学显著性阈值。
Can J Anaesth. 2023 Sep;70(9):1441-1448. doi: 10.1007/s12630-023-02529-9. Epub 2023 Aug 10.
2
The Fragility Index of randomized controlled trials in pediatric anesthesiology.儿科麻醉学随机对照试验的脆弱性指数。
Can J Anaesth. 2023 Sep;70(9):1449-1460. doi: 10.1007/s12630-023-02513-3. Epub 2023 Jun 8.
3
Paediatric surgical trials, their fragility index, and why to avoid using it to evaluate results.
儿科外科试验、脆弱指数及其为何应避免用于评估结果
Pediatr Surg Int. 2022 Jul;38(7):1057-1066. doi: 10.1007/s00383-022-05133-y. Epub 2022 May 7.
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Survival-Inferred Fragility Index of Phase 3 Clinical Trials Evaluating Immune Checkpoint Inhibitors.评估免疫检查点抑制剂的 3 期临床试验的生存推断脆弱指数。
JAMA Netw Open. 2020 Oct 1;3(10):e2017675. doi: 10.1001/jamanetworkopen.2020.17675.