Faculty of Medicine, Menoufia University, Yassin Abdelghaffar Street From Gamal Abdelnaser Street, Shebin Al-Kom, Menoufia, Egypt.
BMC Pregnancy Childbirth. 2023 Nov 21;23(1):807. doi: 10.1186/s12884-023-06094-3.
This network meta-analysis compared different methods to determine which is most efficient at lowering pain and anxiety in women undergoing amniocentesis.
We looked through all published randomized controlled trials in the databases PubMed, Scopus, Web of Science, Cochrane, and EM base. Anxiety and pain were the predominant results. We used the R software version 4.2.1 to analyze the data.
We included a total of 20 studies, with sample sizes ranging from 60 to 570. Virtual reality was the most effective strategy for lowering pain during AC [MD = -1.30, 95% CI (-2.11, -0.49)]. In addition, paracetamol use was the most successful approach for lowering pain following AC [MD = -1.68, 95% CI (-1.99, -1.37)]. The use of H7 acupressure, however, was the strategy that significantly reduced anxiety following AC [SMD = -15.46, 95% CI (-17.77, -13.15)].
The most effective method for reducing pain is the combination of virtual reality with paracetamol. Whereas, the most effective way to reduce anxiety is to combine an ice gel pack with H7 acupressure before applying AC.
本网络荟萃分析比较了不同方法，以确定哪种方法在降低行羊膜穿刺术的女性的疼痛和焦虑方面最有效。
我们在 PubMed、Scopus、Web of Science、Cochrane 和 EM base 数据库中查找了所有已发表的随机对照试验。焦虑和疼痛是主要结果。我们使用 R 软件版本 4.2.1 来分析数据。
我们共纳入 20 项研究，样本量从 60 到 570 不等。虚拟现实是降低 AC 期间疼痛的最有效策略 [MD=-1.30，95%CI（-2.11，-0.49）]。此外，使用扑热息痛是降低 AC 后疼痛的最成功方法 [MD=-1.68，95%CI（-1.99，-1.37）]。然而，使用 H7 穴位按压是降低 AC 后焦虑的有效策略 [SMD=-15.46，95%CI（-17.77，-13.15）]。
降低疼痛最有效的方法是虚拟现实与扑热息痛联合应用。而降低焦虑最有效的方法是在进行 AC 前，将冰袋与 H7 穴位按压相结合。
