Department of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, Corneel Heymanslaan 10, 9000, Ghent, Belgium.
Department of Biochemistry and Microbiology, Faculty of Sciences, Ghent University, K. L. Ledeganckstraat 35, 9000, Ghent, Belgium.
Virol J. 2023 Nov 21;20(1):271. doi: 10.1186/s12985-023-02238-1.
Generally influenza, a contagious respiratory disease, leads to mild illness, but can present as a severe illness with significant complications for some. It entails significant health challenges and an economic burden. Annual vaccination is considered the most effective preventive measure against influenza, especially in high-risk groups.
Epidemiological, demographic and vaccination data of influenza from 2009-to-2019 is collected from Sciensano, the Belgian Institute for Health. Sciensano monitors influenza virus through two surveillances: the Influenza-Like Illness (ILI) surveillance in primary care and the Severe Acute Respiratory Infections (SARI) surveillance in hospital settings.
49.6% [± 8.5] of all ILI-samples tested positive in this period. Influenza A was the dominant circulating type, accounting for 73.7% [± 27.5] of positive samples, while influenza B accounted for 24.3% [± 26.7]. For SARI-surveillance, the average rate of samples tested positive was 36.3% [± 9.3]. Influenza A was responsible for respectively 77.7% [± 23.8] of positive samples and influenza B for 22.2% [± 23.7]. Since 2010, epidemics typically lasted about 9.3 weeks [± 2.7]. From 2012 to 2019 the average vaccine effectiveness was 34.9% [± 15.3].
Influenza is quickly considered a trivial disease, but can have substantial repercussions. It remains difficult to identify the level of treat of influenza due to antigenic evolution. Measures to prevent, control and treat are needed. Vaccines that provide broader and more durable protection that can be produced more rapidly could be a potential solution.
一般来说,流感是一种传染性呼吸道疾病,可导致轻症,但对某些人来说,也可能表现为重症,并伴有严重并发症。它带来了巨大的健康挑战和经济负担。每年接种疫苗被认为是预防流感的最有效措施,尤其是在高风险人群中。
从比利时健康研究所 Sciensano 收集了 2009 年至 2019 年流感的流行病学、人口统计学和疫苗接种数据。Sciensano 通过两种监测来监测流感病毒:初级保健中的流感样疾病(ILI)监测和医院环境中的严重急性呼吸道感染(SARI)监测。
在此期间,所有 ILI 样本的检测阳性率为 49.6%[±8.5]。甲型流感是主要流行类型,占阳性样本的 73.7%[±27.5],乙型流感占 24.3%[±26.7]。对于 SARI 监测,测试阳性样本的平均率为 36.3%[±9.3]。甲型流感分别占阳性样本的 77.7%[±23.8],乙型流感占 22.2%[±23.7]。自 2010 年以来,流感流行通常持续约 9.3 周[±2.7]。2012 年至 2019 年,疫苗平均有效率为 34.9%[±15.3]。
流感很快被认为是一种微不足道的疾病,但可能会产生重大影响。由于抗原进化,仍然难以确定流感的严重程度。需要采取预防、控制和治疗措施。能够更快生产且提供更广泛和更持久保护的疫苗可能是一种潜在的解决方案。