Department of Operative Dentistry, Faculty of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran.
Department of Dental Biomaterials, School of Dentistry/Research Center for Science and Technology in Medicine, University of Medical Sciences, Tehran, Iran.
BMC Oral Health. 2023 Nov 22;23(1):906. doi: 10.1186/s12903-023-03617-4.
The present study aimed to evaluate the flexural strength, degree of conversion, and demineralization-prevention ability of an experimental fissure sealant containing nano-calcium-phosphate compounds.
An experimental sealant was formulated using silica and nano hydroxyapatite filler particles. The control group consisted of the DENU Seal (n = 10, each group). The flexural bond strength was evaluated by UTM. DC was evaluated by FTIR. To evaluate the demineralization-prevention ability, Cl V cavities in 10 third molar teeth restored with two sealant products, followed by an acid challenge then the Vickers microhardness test was carried out.
The mean flexural strength in the commercial group was higher than the experimental group. However, the mean flexural modulus was not significantly different between the two groups. In the experimental group, DC was significantly higher than the commercial group. Adjacent to the interface, the decrease in microhardness in the experimental group was significantly less than the commercial group. However, on the tooth surface, there were no significant differences between the two groups. In the experimental group, the decrease in microhardness at the interface was less than at the tooth surface, however the situation was opposite in the commercial group.
Incorporating hydroxyapatite into the sealant structure might prevent demineralization, without adverse effects on flexural modulus and degree of conversion.
本研究旨在评估一种含有纳米钙磷化合物的实验性窝沟封闭剂的弯曲强度、转化率和防脱矿能力。
采用硅烷和纳米羟基磷灰石填料颗粒配制实验性封闭剂。对照组为 DENU Seal(n=10,每组)。采用 UTM 评估弯曲结合强度,采用 FTIR 评估 DC。为了评估防脱矿能力,对 10 颗第三磨牙上的 Cl V 窝沟进行修复,使用两种封闭剂产品,然后进行酸挑战,再进行维氏显微硬度测试。
商用组的平均弯曲强度高于实验组。然而,两组的平均弯曲模量无显著差异。在实验组中,DC 明显高于商用组。在界面附近,实验组的显微硬度下降明显小于商用组。然而,在牙齿表面,两组之间没有显著差异。在实验组中,界面处的显微硬度下降小于牙齿表面,但商用组的情况则相反。
将羟基磷灰石纳入封闭剂结构中可能会防止脱矿,而不会对弯曲模量和转化率产生不利影响。