MAGI EUREGIO, Bolzano, Italy.
MAGISNAT, Peachtree Corners (GA), USA.
Clin Ter. 2023 Nov-Dec;174(Suppl 2(6)):183-192. doi: 10.7417/CT.2023.2486.
Nutrigenomics, a rapidly evolving field that bridges genetics and nutrition, explores the intricate interactions between an individual's genetic makeup and how they respond to nutrients. At its core, this discipline focuses on investigating Single Nucleotide Polymorphisms (SNPs), the most common genetic variations, which significantly influence a person's physiological status, mood regulation, and sleep patterns, thus playing a pivotal role in a wide range of health out-comes. Through decoding their functional implications, researchers are able to uncover genetic factors that impact physical fitness, pain perception, and susceptibility to mood disorders and sleep disruptions. The integration of nutrigenomics into healthcare holds the promise of transformative interventions that cater to individual well-being. Notable studies shed light on the connection between SNPs and personalized responses to exercise, as well as vulnerability to mood disorders and sleep disturbances. Understanding the intricate interplay between genetics and nutrition informs targeted dietary approaches, molding individual health trajectories. As research advances, the convergence of genetics and nourishment is on the brink of reshaping healthcare, ushering in an era of personalized health management that enhances overall life quality. Nutrigenomics charts a path toward tailored nutritional strategies, fundamentally reshaping our approach to health preservation and preventive measures.
营养基因组学是一个快速发展的领域，它将遗传学和营养学联系起来，探索个体遗传组成与他们对营养的反应之间的复杂相互作用。从本质上讲，该学科专注于研究单核苷酸多态性（SNPs），这是最常见的遗传变异，它们显著影响一个人的生理状态、情绪调节和睡眠模式，从而在广泛的健康结果中发挥关键作用。通过解码其功能意义，研究人员能够揭示影响身体健康、疼痛感知以及易患情绪障碍和睡眠障碍的遗传因素。将营养基因组学纳入医疗保健有望实现针对个体健康的变革性干预。值得注意的研究揭示了 SNPs 与对运动的个性化反应以及对情绪障碍和睡眠障碍的易感性之间的联系。了解遗传和营养之间的复杂相互作用为有针对性的饮食方法提供了信息，塑造了个体的健康轨迹。随着研究的进展，遗传学和营养的融合即将重塑医疗保健，迎来个性化健康管理的时代，提高整体生活质量。营养基因组学为量身定制的营养策略绘制了蓝图，从根本上重塑了我们对健康保护和预防措施的方法。
