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植物化学特征与生物活性:系统综述

Phytochemical Characterization and Biological Activities: A Systematic Review.

作者信息

Laranjeira Inês Martins, Dias Alberto Carlos Pires, Pinto-Ribeiro Filipa Lacerda

机构信息

Life and Health Sciences Research Institute (ICVS), School of Medicine, Campus of Gualtar, University of Minho, 4710-057 Braga, Portugal.

ICVS/3B's-PT Government Associate Laboratory, 4806-909 Guimarães, Portugal.

出版信息

Biology (Basel). 2023 Oct 30;12(11):1387. doi: 10.3390/biology12111387.

DOI:10.3390/biology12111387
PMID:37997986
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10669091/
Abstract

(L.) Willk., known as "prickled broom", is a Leguminosae (Fabaceae) species native to the Iberian Peninsula, Morocco, Algeria, and Tunisia. It is used in folk medicine as an anti-inflammatory, for gastrointestinal and respiratory disorders, rheumatism, and headaches, to lower blood pressure, against hypercholesterolemia and hyperglycemia. This study aimed to systematically review the literature on the bioactivities and phytochemical profile of to understand its pharmacological potential. For this, four electronic databases (PubMed, GoogleScholar, Repositórios Cientificos de Acesso Aberto de Portugal (RCCAP), and ScienceDirect) were searched from inception up to 31 December 2022. From a total of 264 potentially eligible studies considered for screening, 34 papers were considered eligible for this systematic review. The sampling included 71 extracts, collected mainly in Portugal. extracts present a high level of flavonoids and phenolic compounds. The flowers and aerial parts of the plant were the most studied, and aqueous extracts were the most used. The results predict a high potential for the application of as a new source of natural antioxidants and preservatives for the food industry with subsequent health benefits, such as the production of nutraceuticals. Moreover, the results indicate that the plant can be collected at all seasons of the year, which represents a benefit for the industry.

摘要

刺金雀(L.)威尔克,又名“多刺金雀”,是一种豆科(豆科)植物,原产于伊比利亚半岛、摩洛哥、阿尔及利亚和突尼斯。它在民间医学中被用作抗炎药,用于治疗胃肠道和呼吸道疾病、风湿病和头痛,还可用于降低血压、对抗高胆固醇血症和高血糖症。本研究旨在系统回顾关于刺金雀生物活性和植物化学特征的文献,以了解其药理潜力。为此,检索了四个电子数据库(PubMed、谷歌学术、葡萄牙开放获取科学存储库(RCCAP)和科学Direct),检索时间从数据库创建至2022年12月31日。在总共264项考虑用于筛选的潜在合格研究中,有34篇论文被认为符合本系统评价的要求。样本包括71种提取物,主要采集于葡萄牙。提取物中黄酮类化合物和酚类化合物含量较高。该植物的花和地上部分研究最多,水提取物使用最频繁。结果预测,刺金雀作为食品工业新的天然抗氧化剂和防腐剂来源具有很高的应用潜力,并具有后续的健康益处,如生产营养保健品。此外,结果表明该植物一年中四季均可采集,这对该行业来说是一个优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58ea/10669091/dae64e60c88a/biology-12-01387-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58ea/10669091/f33c58a89cfd/biology-12-01387-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58ea/10669091/dae64e60c88a/biology-12-01387-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58ea/10669091/f33c58a89cfd/biology-12-01387-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58ea/10669091/dae64e60c88a/biology-12-01387-g002.jpg

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本文引用的文献

1
From Tradition to Health: Chemical and Bioactive Characterization of Five Traditional Plants.从传统到健康:五种传统植物的化学成分和生物活性分析。
Molecules. 2022 Oct 1;27(19):6495. doi: 10.3390/molecules27196495.
2
Automatic Identification of Myeloperoxidase Natural Inhibitors in Plant Extracts.自动鉴定植物提取物中的髓过氧化物酶天然抑制剂。
Molecules. 2022 Mar 11;27(6):1825. doi: 10.3390/molecules27061825.
3
Multitarget protection of Pterospartum tridentatum phenolic-rich extracts against a wide range of free radical species, antidiabetic activity and effects on human colon carcinoma (Caco-2) cells.
对总状绿绒蒿富多酚提取物的多靶点保护作用,针对多种自由基种类,抗糖尿病活性以及对人结肠癌细胞(Caco-2)的影响。
J Food Sci. 2020 Dec;85(12):4377-4388. doi: 10.1111/1750-3841.15511. Epub 2020 Oct 29.
4
L.: A Rich Source of Flavonoids with Anti-inflammatory Activity.L.:一种具有抗炎活性的黄酮类化合物的丰富来源。
Medicines (Basel). 2020 May 30;7(6):31. doi: 10.3390/medicines7060031.
5
Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis.表达 HCN4 的胃肠道神经元调节逆行蠕动。
Cell Rep. 2020 Mar 3;30(9):2879-2888.e3. doi: 10.1016/j.celrep.2020.02.024.
6
Flavonoid Profile of the L., a Species Used Traditionally to Treat Inflammatory Processes.传统用于治疗炎症过程的 L. 物种的类黄酮特征。
Molecules. 2020 Feb 13;25(4):812. doi: 10.3390/molecules25040812.
7
Challenges of traditional herbal teas: plant infusions and their mixtures with bioactive properties.传统草药茶的挑战:植物浸剂及其与生物活性成分的混合物。
Food Funct. 2019 Sep 1;10(9):5939-5951. doi: 10.1039/c9fo01473j. Epub 2019 Aug 30.
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Rutin protects mercuric chloride-induced nephrotoxicity via targeting of aquaporin 1 level, oxidative stress, apoptosis and inflammation in rats.芦丁通过靶向水通道蛋白 1 水平、氧化应激、细胞凋亡和炎症来保护氯化汞诱导的肾毒性。
J Trace Elem Med Biol. 2019 Jul;54:69-78. doi: 10.1016/j.jtemb.2019.04.007. Epub 2019 Apr 18.
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A Guide for Systematic Reviews: PRISMA.系统评价指南:PRISMA
Turk Arch Otorhinolaryngol. 2019 Mar;57(1):57-58. doi: 10.5152/tao.2019.4058. Epub 2019 Mar 14.
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Inhibitory effect of taxifolin on mast cell activation and mast cell-mediated allergic inflammatory response.山奈酚对肥大细胞活化及肥大细胞介导的过敏炎症反应的抑制作用。
Int Immunopharmacol. 2019 Jun;71:205-214. doi: 10.1016/j.intimp.2019.03.038. Epub 2019 Mar 26.