Scalia Isabel G, Farina Juan M, Padang Ratnasari, Jokerst Clinton E, Pereyra Milagros, Mahmoud Ahmed K, Naqvi Tasneem Z, Chao Chieh-Ju, Oh Jae K, Arsanjani Reza, Ayoub Chadi
Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
J Imaging. 2023 Nov 15;9(11):250. doi: 10.3390/jimaging9110250.
Aortic valve stenosis (AS) is increasing in prevalence due to the aging population, and severe AS is associated with significant morbidity and mortality. Echocardiography remains the mainstay for the initial detection and diagnosis of AS, as well as for grading of severity. However, there are important subgroups of patients, for example, patients with low-flow low-gradient or paradoxical low-gradient AS, where quantification of severity of AS is challenging by echocardiography and underestimation of severity may delay appropriate management and impart a worse prognosis. Aortic valve calcium score by computed tomography has emerged as a useful clinical diagnostic test that is complimentary to echocardiography, particularly in cases where there may be conflicting data or clinical uncertainty about the degree of AS. In these situations, aortic valve calcium scoring may help re-stratify grading of severity and, therefore, further direct clinical management. This review presents the evolution of aortic valve calcium score by computed tomography, its diagnostic and prognostic value, as well as its utility in clinical care.
由于人口老龄化,主动脉瓣狭窄(AS)的患病率正在上升,重度AS与显著的发病率和死亡率相关。超声心动图仍然是AS初始检测、诊断以及严重程度分级的主要手段。然而,存在一些重要的患者亚组,例如低流量低梯度或矛盾性低梯度AS患者,对于这些患者,通过超声心动图对AS严重程度进行量化具有挑战性,并且严重程度的低估可能会延迟适当的治疗并导致更差的预后。计算机断层扫描的主动脉瓣钙化评分已成为一种有用的临床诊断测试,它是对超声心动图的补充,特别是在关于AS程度可能存在相互矛盾的数据或临床不确定性的情况下。在这些情况下,主动脉瓣钙化评分可能有助于重新分层严重程度分级,从而进一步指导临床治疗。本综述介绍了计算机断层扫描主动脉瓣钙化评分的演变、其诊断和预后价值以及在临床护理中的效用。