Liu Min, Liu Bifu, Wang Qian, Feng Kejun, Li Yuanhua, Liu Lixin, Tong Jiaen
School of Chemistry and Materials Engineering, Huizhou University, Huizhou 516007, China.
Guangdong Provincial Key Laboratory of Electronic Functional Materials and Devices, Huizhou University, Huizhou 516001, Guangdong, P. R. China.
Org Biomol Chem. 2024 Jan 24;22(4):699-702. doi: 10.1039/d3ob01403g.
A novel and efficient metal-free cascade oxidative radical addition of styrenes is developed for the construction of 1,3-dichloro-1,5-diarylpentan-5-ones. This protocol presents a practical one-pot procedure that delivers highly functionalized 1,3-dichloro-1,5-diarylpentan-5-ones in moderate-to-good yields with a broad substrate scope under mild conditions.
开发了一种新颖且高效的无金属级联氧化自由基加成反应，用于构建1,3-二氯-1,5-二芳基戊-5-酮。该方法提供了一种实用的一锅法，在温和条件下以中等到良好的产率得到具有广泛底物范围的高度官能化的1,3-二氯-1,5-二芳基戊-5-酮。
