Laboratory of Bioactive and Molecules of Interest, National Agency of Medicinal and Aromatic Plants (NAMAP), Taounate 34000, Morocco.
Department of Safety and Quality of Cereals, Max Rubner-Institut, Federal Research Insitute for Nutrition and Food, Schützenberg 12, D-32756 Detmold, Germany.
Biomolecules. 2023 Nov 20;13(11):1675. doi: 10.3390/biom13111675.
Petroselinic fatty acid (PeFA) is considered a rare fatty acid and one of the most important fatty acids in the Apiaceae family. Its content varies depending on plant species, geographical origin, extraction method, ripeness, etc. Indeed, reported levels of petroselinic fatty acid range from 10.4 to 75.6% (in anise seed oil), 1 to 81.9% (in coriander seed oil), 28.5 to 57.6% (in caraway seed oil), 49.4 to 75.6% (in celery seed oil), 41.3 to 61.8% (in caraway seed oil), 79.9 to 87.2% (in dill seed oil), 43.1 to 81.9% (in fennel seed oil), and 35 to 75.1% (parsley seed oil). In this review, we also show current knowledge about genes encoding biosynthesis, from the desaturation of 16:0-ACP to petroselinic acid stored in triacylglycerol in the seeds. Furthermore, petroselinic acid is not related to the synthesis of ABA. PeFA was successfully isolated from Apiaceae family plant seeds in order to study their reactivity and biological activities. Several investigations showed that this fatty acid has a wide range of biological potentials, including antidiabetic, antibacterial, and antifungal activities. In cosmetics, PeFA alone or in association with other active compounds has interesting applications as an anti-inflammatory agent for the treatment of skin, hair, and nail disorders.
芹菜酸(PeFA)被认为是一种稀有脂肪酸,也是伞形科植物中最重要的脂肪酸之一。其含量因植物种类、地理来源、提取方法、成熟度等因素而异。实际上,已报道的芹菜酸含量范围为 10.4%至 75.6%(在大茴香籽油中)、1%至 81.9%(在芫荽籽油中)、28.5%至 57.6%(在葛缕子籽油中)、49.4%至 75.6%(在芹菜籽油中)、41.3%至 61.8%(在葛缕子籽油中)、79.9%至 87.2%(在莳萝籽油中)、43.1%至 81.9%(在茴香籽油中),以及 35%至 75.1%(西芹籽油)。在这篇综述中,我们还展示了目前关于编码生物合成的基因的知识,从 16:0-ACP 的去饱和作用到储存在种子三酰基甘油中的芹菜酸。此外,芹菜酸与 ABA 的合成无关。成功地从伞形科植物种子中分离出 PeFA,以研究其反应性和生物活性。多项研究表明,这种脂肪酸具有广泛的生物学潜力,包括抗糖尿病、抗菌和抗真菌活性。在化妆品中,PeFA 单独或与其他活性化合物联合使用,具有作为抗炎剂治疗皮肤、头发和指甲疾病的有趣应用。