Heavy Ion Laboratory, University of Warsaw, Pasteura 5a, 02-093 Warsaw, Poland.
Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.
Molecules. 2023 Nov 19;28(22):7668. doi: 10.3390/molecules28227668.
The concept of theranostics uses radioisotopes of the same or chemically similar elements to label biological ligands in a way that allows the use of diagnostic and therapeutic radiation for a combined diagnosis and treatment regimen. For scandium, radioisotopes -43 and -44 can be used as diagnostic markers, while radioisotope scandium-47 can be used in the same configuration for targeted therapy. This work presents the latest achievements in the production and processing of radioisotopes and briefly characterizes solutions aimed at increasing the availability of these radioisotopes for research and clinical practice.
治疗诊断学的概念使用同种或化学性质类似的元素的放射性同位素来标记生物配体，以便将诊断和治疗辐射用于联合诊断和治疗方案。对于钪，可以使用放射性同位素-43 和-44 作为诊断标记物，而放射性同位素钪-47 可以以相同的方式用于靶向治疗。本工作介绍了放射性同位素的生产和加工的最新成果，并简要描述了旨在增加这些放射性同位素在研究和临床实践中可用性的解决方案。
