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中国医护人员对新冠病毒疫苗第二剂加强针的犹豫态度:一项多中心横断面研究

The second dose of COVID-19 vaccine booster hesitancy among health care workers in China: A multicenter cross-sectional study.

作者信息

Zhang Ling, Wu Yijin, Jing Shu, Liu Xin, Ren Tianrui, Liu Xiaoyang, Dai Zhenwei, Fu Jiaqi, Chen Xu, Xiao Weijun, Huang Yiman, Wang Hao, Wang Wenjun, Gu Xiaofen, Ma Li, Zhang Shaokai, Yu Yanqin, Li Li, Su Xiaoyou, Qiao Youlin

机构信息

School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

School of Nursing, Jining Medical University, Jining, Shandong, China.

出版信息

Am J Infect Control. 2024 May;52(5):525-532. doi: 10.1016/j.ajic.2023.11.012. Epub 2023 Nov 23.

DOI:10.1016/j.ajic.2023.11.012
PMID:38007100
Abstract

BACKGROUND

The COVID-19 outbreak in China exposed health care workers (HCWs) to an increased risk of infection. The acquired immunity rapidly diminishes after the previous COVID-19 vaccination and the second booster vaccination has been recommended in several countries. HCWs are a priority group for vaccination because they are at increased risk of being infected, however, a certain amount of HCWs were hesitant.

METHODS

The survey was conducted among 5805 HCWs in China from January 5 to February 9, 2023. Questionnaire included sociodemographic information, COVID-19-related variables, psychological factors, and the COVID-19 vaccine hesitancy scale. Multiple logistic regression analysis was used to assess the influencing factors of the second dose of COVID-19 vaccine booster hesitancy.

RESULTS

42.2% of HCWs self-reported having the second dose of COVID-19 vaccine booster hesitancy. Occupations, years of working, COVID-19 infection status were associated with less vaccine hesitancy. HCWs who had received 3 doses of COVID-19 vaccine were less likely to be hesitant compared to those had not received. HCWs with PTSD symptoms and anxiety symptoms were more likely to be hesitant. No relation was observed between COVID-19 vaccine booster hesitancy and age, marriage, salary, and perceived an increased risk of COVID-19 infection due to work (all P > 0.05).

CONCLUSIONS

A considerable proportion of HCWs were hesitant to accept the second dose of the COVID-19 booster vaccine. Incorporating vaccine knowledge and new evidence into routine health educations and procedures to raise confidence and reduce complacency may be effective and feasible in promoting the vaccination and implementing future vaccination programs.

摘要

背景

中国的新冠疫情使医护人员面临更高的感染风险。先前接种新冠疫苗后获得的免疫力会迅速下降,一些国家已建议进行第二次加强接种。医护人员是疫苗接种的优先群体,因为他们感染风险较高,然而,仍有一定数量的医护人员对此犹豫不决。

方法

2023年1月5日至2月9日对中国5805名医护人员进行了调查。问卷包括社会人口学信息、新冠相关变量、心理因素以及新冠疫苗犹豫量表。采用多因素logistic回归分析评估新冠疫苗第二剂加强接种犹豫的影响因素。

结果

42.2%的医护人员自我报告有新冠疫苗第二剂加强接种犹豫。职业、工作年限、新冠感染状况与较低的疫苗犹豫相关。与未接种3剂新冠疫苗的医护人员相比,接种过3剂的医护人员犹豫的可能性较小。有创伤后应激障碍症状和焦虑症状的医护人员更有可能犹豫。未观察到新冠疫苗加强接种犹豫与年龄、婚姻状况、薪资以及因工作而感知到的新冠感染风险增加之间存在关联(所有P>0.05)。

结论

相当一部分医护人员对接受新冠疫苗第二剂加强接种犹豫不决。将疫苗知识和新证据纳入常规健康教育和程序,以增强信心并减少自满情绪,可能在促进疫苗接种和实施未来疫苗接种计划方面有效且可行。

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