Evidence-based Medicine Center, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai, Zhejiang, China.
Taizhou Institute of Medicine, Health and New Drug Clinical Research, Taizhou, China.
BMC Infect Dis. 2024 Oct 2;24(1):1095. doi: 10.1186/s12879-024-09917-6.
This research aimed to explore hesitation towards the COVID-19 booster vaccine among dialysis patients and study the association between COVID-19 pandemic-induced health behavior and vaccination hesitancy.
A self-administered online questionnaire evaluating dialysis patients' hesitation to take COVID-19 booster vaccination was conducted between March 24 and 22 April 2022 in Taizhou, China. The logistic regression method was applied to identify factors associated with vaccination hesitancy, and all data were analyzed using R software.
Of the 365 study participants, 272 (74.5%) individuals hesitated to take the booster dose. Health behavior was found to be a significant factor for hesitation to take COVID-19 vaccines, with OR (95% CI) of 1.09 (1.02-1.17). Influenza vaccination history was also significantly associated with the hesitation (OR (95% CI) = 0.39 (0.21-0.74)). In addition, participants with higher education levels exhibited lower vaccine hesitancy compared to those with junior secondary or below, with ORs (95% CIs) of 0.49 (0.27-0.91) for senior secondary and 0.35 (0.14-0.89) for junior college or above, respectively.
The proportion of hesitancy for taking the booster vaccination of the COVID-19 vaccine was high among dialysis patients. Health behaviors, influenza vaccination history, and education levels were risk factors in their vaccination hesitancy. These findings may aid efforts to help vaccinate people with underlying diseases against future pandemics.
本研究旨在探讨透析患者对 COVID-19 加强疫苗的犹豫态度,并研究 COVID-19 大流行引起的健康行为与疫苗犹豫之间的关系。
2022 年 3 月 24 日至 4 月 22 日,在中国台州,通过在线自填问卷评估了透析患者对接种 COVID-19 加强疫苗的犹豫程度。采用逻辑回归方法确定与疫苗犹豫相关的因素,所有数据均使用 R 软件进行分析。
在 365 名研究参与者中,有 272 名(74.5%)个体对接种加强剂量犹豫不决。健康行为是对 COVID-19 疫苗犹豫不决的重要因素,比值比(95%置信区间)为 1.09(1.02-1.17)。流感疫苗接种史也与犹豫不决显著相关(比值比(95%置信区间)=0.39(0.21-0.74))。此外,与具有初中及以下学历的参与者相比,具有较高教育水平的参与者对疫苗的犹豫程度较低,高中(95%置信区间 0.49(0.27-0.91))和大专及以上(95%置信区间 0.35(0.14-0.89))的比值比分别为 0.49(0.27-0.91)和 0.35(0.14-0.89)。
透析患者对接种 COVID-19 加强疫苗的犹豫比例较高。健康行为、流感疫苗接种史和教育水平是他们疫苗犹豫的危险因素。这些发现可能有助于为未来的大流行接种有潜在疾病的人群。