不同几何形态下颅内动脉瘤破裂风险的血流动力学分析的计算方法的应用。

Institute of Research and Development, Duy Tan University, Da Nang, Vietnam.

School of Engineering and Technology, Duy Tan University, Da Nang, Vietnam.

Sci Rep. 2023 Nov 25;13(1):20749. doi: 10.1038/s41598-023-48246-7.

The importance of the parent vessel geometrical feature on the risk of cerebral aneurysm rupture is unavoidable. This study presents inclusive details on the hemodynamics of Internal carotid artery (ICA) aneurysms with different parent vessel mean diameters. Different aspects of blood hemodynamics are compared to find a reasonable connection between parent vessel mean diameter and significant hemodynamic factors of wall shear stress (WSS), oscillatory shear index (OSI), and pressure distribution. To access hemodynamic data, computational fluid dynamics is used to model the blood stream inside the cerebral aneurysms. A hemodynamic comparison of the selected cerebral aneurysm shows that the minimum WSS is reduced by about 71% as the parent vessel's mean diameter is increased from 3.18 to 4.48 mm.

血管母体的几何特征对于颅内动脉瘤破裂风险的重要性是不可避免的。本研究详细介绍了不同母体血管平均直径的颈内动脉（ICA）动脉瘤的血液动力学。比较了血液动力学的不同方面，以找到母体血管平均直径与壁切应力（WSS）、振荡剪切指数（OSI）和压力分布等重要血流动力学因素之间的合理联系。为了获取血液动力学数据，使用计算流体动力学来模拟颅内动脉瘤内的血流。对所选颅内动脉瘤的血液动力学比较表明，当母体血管的平均直径从 3.18 毫米增加到 4.48 毫米时，最小壁切应力降低了约 71%。