Department of Space, Earth and Environment, Chalmers University of Technology, Gothenburg, Sweden.
Department of Mechanical Engineering, Babol Noshirvani University of Technology, Babol, Iran.
Biomech Model Mechanobiol. 2023 Aug;22(4):1193-1207. doi: 10.1007/s10237-023-01710-9. Epub 2023 Mar 22.
One of the effective treatment options for intracranial aneurysms is stent-assisted coiling. Though, previous works have demonstrated that stent usage would result in the deformation of the local vasculature. The effect of simple stent on the blood hemodynamics is still uncertain. In this work, hemodynamic features of the blood stream on four different ICA aneurysm with/without interventional are investigated. To estimate the relative impacts of vessel deformation, four distinctive ICA aneurysm is simulated by the one-way FSI technique. Four hemodynamic factors of aneurysm blood velocity, wall pressure and WSS are compared in the peak systolic stage to disclose the impact of defamation by the stent in two conditions. The stent usage would decrease almost all of the mentioned parameters, except for OSI. Stenting reduces neck inflow rate, while the effect of interventional was not consistent among the aneurysms. The deformation of an aneurysm has a strong influence on the hemodynamics of an aneurysm. This outcome is ignored by most of the preceding investigations, which focused on the pre-interventional state for studying the relationship between hemodynamics and stents. Present results show that the application of stent without coiling would improve most hemodynamic factors, especially when the deformation of the aneurysm is high enough.
颅内动脉瘤的有效治疗方法之一是支架辅助线圈。然而,以前的研究表明,支架的使用会导致局部血管变形。简单支架对血液动力学的影响尚不确定。在这项工作中,研究了四种不同的 ICA 动脉瘤(有/无介入治疗)的血流动力学特征。为了评估血管变形的相对影响,采用单向 FS I 技术模拟了四个不同的 ICA 动脉瘤。在收缩期峰值阶段比较了动脉瘤血流速度、壁压和 WSS 四个血流动力学因素,以揭示支架在两种情况下对变形的影响。支架的使用几乎会降低所有提到的参数,除了 OSI。支架可以减少颈部流入率,而介入治疗对动脉瘤的影响在不同的动脉瘤之间并不一致。动脉瘤的变形对动脉瘤的血流动力学有很强的影响。这一结果被大多数以前的研究所忽略,这些研究主要集中在介入前状态,以研究血流动力学与支架之间的关系。目前的结果表明,支架的应用而不进行线圈可以改善大多数血流动力学因素,尤其是当动脉瘤的变形足够高时。