Espinal J, Beggs M, Patel H, Randle P J
Biochem J. 1986 Jul 1;237(1):285-8. doi: 10.1042/bj2370285.
The activity of branched-chain 2-oxo acid dehydrogenase kinase was 3-fold greater in extracts of heart mitochondria than in extracts of liver mitochondria from rats fed on normal diet. Feeding rats on a 0%-casein diet for 10 days increased the activity of branched-chain kinase 4-fold in extracts of liver mitochondria and in branched-chain dehydrogenase complex purified from such extracts; starvation (48 h) was without effect. In extract of heart mitochondria, kinase activity was increased 2-fold by feeding on 0%-casein diet and 1.5-fold by 48 h of starvation.
在以正常饮食喂养的大鼠中，心脏线粒体提取物中支链2-氧代酸脱氢酶激酶的活性比肝脏线粒体提取物中的活性高3倍。给大鼠喂食0%酪蛋白饮食10天，可使肝脏线粒体提取物以及从此类提取物中纯化的支链脱氢酶复合物中的支链激酶活性增加4倍；饥饿（48小时）则没有影响。在心脏线粒体提取物中，喂食0%酪蛋白饮食可使激酶活性增加2倍，饥饿48小时可使其增加1.5倍。
