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髂嵴活检:矿化骨量的代表性

Iliac crest biopsy: representativity for the amount of mineralized bone.

作者信息

Pødenphant J, Gotfredsen A, Nilas L, Nørgaard H, Braendstrup O

出版信息

Bone. 1986;7(6):427-30. doi: 10.1016/8756-3282(86)90002-5.

DOI:10.1016/8756-3282(86)90002-5
PMID:3801235
Abstract

The aim of the study was to evaluate the representativity of iliac crest biopsy for the amount of mineralized trabecular and cortical bone in the skeleton. The following data were obtained on bone from 14 necropsies: right sided iliac crest biopsy, lumbar spine biopsy, dry fat free weight of lumbar spine, bone mineral density (BMD) in the lumbar spine and dry fat free weight of cortical and trabecular bone from the left distal forearm. The amount of mineralized cortical and trabecular bone from various sites was compared by linear regression analysis. The results confirm iliac crest biopsy as a good predictor of the amount of trabecular bone, but not of cortical bone. Furthermore, iliac crest biopsy is a better estimate of the amount of trabecular bone in the lumbar spine than spinal BMD.

摘要

本研究的目的是评估髂嵴活检对于骨骼中矿化小梁骨和皮质骨数量的代表性。从14例尸检的骨骼中获取了以下数据:右侧髂嵴活检、腰椎活检、腰椎去脂干重、腰椎骨密度(BMD)以及左前臂远端皮质骨和小梁骨的去脂干重。通过线性回归分析比较了不同部位矿化皮质骨和小梁骨的数量。结果证实髂嵴活检是小梁骨数量的良好预测指标,但不是皮质骨数量的良好预测指标。此外,与脊柱骨密度相比,髂嵴活检能更好地估计腰椎小梁骨的数量。

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Iliac crest biopsy: representativity for the amount of mineralized bone.髂嵴活检:矿化骨量的代表性
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Interindividual and intraspecimen variability of 3-D bone microarchitectural parameters in iliac crest biopsies imaged by conventional micro-computed tomography.
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Osteoporos Int. 1993 Mar;3(2):90-6. doi: 10.1007/BF01623379.
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Interleukin-1 receptor antagonist decreases bone loss and bone resorption in ovariectomized rats.白细胞介素-1受体拮抗剂可减少去卵巢大鼠的骨质流失和骨吸收。
J Clin Invest. 1994 May;93(5):1959-67. doi: 10.1172/JCI117187.