Department of Zoology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, India.
Phytother Res. 2024 Feb;38(2):755-775. doi: 10.1002/ptr.8079. Epub 2023 Nov 28.
The metabolic syndrome (MetS) refers to the co-occurrence of risk factors, including hyperglycaemia, increased body weight, hypertension and dyslipidemia, which eventually lead to diabetes and cardiovascular disease, a common health problem worldwide. Recently, there has been an increasing interest in the use of plant-based products for the management of MetS, because of their less detrimental and more beneficial effects. Moringa oleifera (Moringaceae), commonly known as drumstick, is cultivated worldwide for its nutritional and medicinal properties. This review focuses on the in vivo and human studies concerning the potential of M. oleifera in the alleviation of MetS and its comorbidities. The search for relevant articles was carried out in PubMed and Google Scholar databases. Randomised controlled and clinical trials from the PubMed database were included in this review. The results suggested that the administration of M. oleifera, in vivo, shows clear signs of improvement in MetS indices. Despite fewer human studies, the existing data documented convincing results that uphold the potential of M. oleifera against MetS. Therefore, future research discussing the probable mechanism of action is much needed which could further assure the usage of M. oleifera in the treatment regimen of MetS.
代谢综合征（MetS）是指多种危险因素同时存在，包括高血糖、体重增加、高血压和血脂异常，最终导致糖尿病和心血管疾病，这是全球普遍存在的健康问题。最近，人们越来越关注使用植物产品来管理代谢综合征，因为它们的副作用较小，有益作用更多。辣木（辣木科），俗称鼓槌，因其营养和药用特性而在全球范围内种植。本综述重点介绍了辣木在缓解代谢综合征及其合并症方面的体内和人体研究。在 PubMed 和 Google Scholar 数据库中进行了相关文章的检索。本综述纳入了来自 PubMed 数据库的随机对照和临床试验。结果表明，辣木在体内给药时，对代谢综合征指标有明显的改善迹象。尽管人体研究较少，但现有数据记录了令人信服的结果，支持辣木对代谢综合征的潜在作用。因此，需要进一步的研究来讨论其可能的作用机制，以进一步确保辣木在代谢综合征的治疗方案中的使用。
