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经盲目肝脏活检证实为伴有门静脉肿瘤血栓形成的转移性乳头状肾细胞癌。

Metastatic papillary renal cell carcinoma with portal vein tumor thrombosis confirmed on blind liver biopsy.

作者信息

Kim Hun, Roh Tae Hoon, Lee Jun Seop, Kim Min Seong, Kim Beom Kyung

机构信息

Department of Medicine, Yonsei University College of Medicine, Seoul, Korea.

Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

出版信息

J Liver Cancer. 2024 Mar;24(1):113-117. doi: 10.17998/jlc.2023.11.05. Epub 2023 Nov 29.

DOI:10.17998/jlc.2023.11.05
PMID:38017367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10990669/
Abstract

Portal vein tumor thrombosis (PVTT) is an uncommon condition in which tumor cells expand into the vessels, causing blood clot formation in the portal vein. PVTT is mainly associated with hepatocellular carcinoma, leading to an unfavorable prognosis; however, it can also develop in patients with other cancer types. Herein, we report a case of metastatic renal cell carcinoma diagnosed by a blind liver biopsy in a patient with dynamic computed tomography-confirmed portal vein thrombosis and cholangiopathy. This case illustrates the importance of systematic surveillance with routine laboratory tests and contrast-enhanced imaging studies on patients with cancer to detect potential liver infiltration of metastatic cancer.

摘要

门静脉肿瘤血栓形成(PVTT)是一种罕见的病症,肿瘤细胞侵入血管,导致门静脉内形成血栓。PVTT主要与肝细胞癌相关,导致预后不良;然而,它也可发生于其他癌症类型的患者。在此,我们报告一例经动态计算机断层扫描确诊为门静脉血栓形成和胆管病的患者,通过盲法肝活检诊断为转移性肾细胞癌。该病例说明了对癌症患者进行常规实验室检查和对比增强成像研究以检测转移性癌症潜在肝浸润的系统监测的重要性。

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本文引用的文献

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2
Prevalence, Treatment, and Prognosis of Tumor Thrombi in Renal Cell Carcinoma.肾细胞癌中肿瘤血栓的患病率、治疗及预后
JACC CardioOncol. 2022 Nov 15;4(4):522-531. doi: 10.1016/j.jaccao.2022.07.011. eCollection 2022 Nov.
3
Portal vein thrombosis: A concise review (Review).门静脉血栓形成:简要综述(综述)
Exp Ther Med. 2021 Jul;22(1):759. doi: 10.3892/etm.2021.10191. Epub 2021 May 13.
4
Papillary renal cell carcinoma: Review.乳头状肾细胞癌:综述。
Urol Oncol. 2021 Jun;39(6):327-337. doi: 10.1016/j.urolonc.2021.04.013. Epub 2021 May 24.
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Treatment of hepatocellular carcinoma in patients with portal vein tumor thrombosis: Beyond the known frontiers.肝细胞癌伴门静脉癌栓患者的治疗:超越已知的边界。
World J Gastroenterol. 2019 Aug 21;25(31):4360-4382. doi: 10.3748/wjg.v25.i31.4360.
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Characterizing the outcomes of metastatic papillary renal cell carcinoma.转移性乳头状肾细胞癌的预后特征分析。
Cancer Med. 2017 May;6(5):902-909. doi: 10.1002/cam4.1048. Epub 2017 Apr 16.
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