噬菌体iGC_PHA_EC001的全基因组序列
Complete genome sequence of phage iGC_PHA_EC001.
作者信息
Khan Tahsin, Haider Arefeen, Rahman Sezanur, Moon Shovan Basak, Mahamud Imtiaz, Mondal Shakhinur Islam, Begum Anowara, Biswas Sudhangshu Kumar, Jubair Mohammad, Rahman Mustafizur
机构信息
Genome Centre, Infectious Diseases Division, icddr,b, Mohakhali , Dhaka, Bangladesh.
Virology Laboratory, Infectious Diseases Division, icddr,b, Mohakhali , Dhaka, Bangladesh.
出版信息
Microbiol Resour Announc. 2024 Jan 17;13(1):e0084223. doi: 10.1128/MRA.00842-23. Epub 2023 Nov 29.
Antimicrobial resistance (AMR) in bacteria poses a global health emergency due to limited treatment options. Here, we report a lytic bacteriophage belonging to family against an AMR (ST2089). phage iGC_PHA_EC001 is of genus and 148,445 bp in length, encoding 269 predicted protein-coding sequences and 10 tRNAs. The phage encodes two lytic proteins containing phage_lysozyme (PF00959.22) and cell wall hydrolase_2 (PF07486.15) as catalytic domains, respectively.
由于治疗选择有限，细菌中的抗菌药物耐药性（AMR）构成了全球卫生紧急情况。在此，我们报告了一种属于 科的裂解性噬菌体，它针对一种AMR （ST2089）。噬菌体iGC_PHA_EC001属于 属，长度为148,445 bp，编码269个预测的蛋白质编码序列和10个tRNA。该噬菌体编码两种裂解蛋白，分别含有噬菌体溶菌酶（PF00959.22）和细胞壁水解酶_2（PF07486.15）作为催化结构域。
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